Skithiryx, the Blight Dragon (Commander) - Budget Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
68decks
As CommanderAs CardAverage DeckDecks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Plague Stinger
87%inclusion59 decks68 decks
86%synergy
Core Prowler
76%inclusion52 decks68 decks
76%synergy
Infectious Inquiry
76%inclusion52 decks68 decks
74%synergy
Plague Myr
74%inclusion50 decks68 decks
72%synergy
Corpse Cur
72%inclusion49 decks68 decks
72%synergy
Reaper of Sheoldred
71%inclusion48 decks68 decks
70%synergy
Vraska's Fall
72%inclusion49 decks68 decks
68%synergy
Whispering Specter
66%inclusion45 decks68 decks
65%synergy
Blightbelly Rat
69%inclusion47 decks68 decks
65%synergy
Drown in Ichor
69%inclusion47 decks68 decks
65%synergy
Top Cards
Ichor Rats
68%inclusion46 decks68 decks
65%synergy
Flensermite
65%inclusion44 decks68 decks
64%synergy
Lashwrithe
63%inclusion43 decks68 decks
59%synergy
Howl from Beyond
63%inclusion43 decks68 decks
62%synergy
Bilious Skulldweller
63%inclusion43 decks68 decks
62%synergy
Ichorclaw Myr
63%inclusion43 decks68 decks
63%synergy
Fireshrieker
63%inclusion43 decks68 decks
61%synergy
Sign in Blood
63%inclusion43 decks68 decks
27%synergy
Hand of the Praetors
62%inclusion42 decks68 decks
61%synergy
Flesh-Eater Imp
60%inclusion41 decks68 decks
60%synergy
Creatures
Septic Rats
57%inclusion39 decks68 decks
55%synergy
Pestilent Syphoner
54%inclusion37 decks68 decks
54%synergy
Necropede
53%inclusion36 decks68 decks
53%synergy
Contagious Nim
47%inclusion32 decks68 decks
47%synergy
Blackcleave Goblin
47%inclusion32 decks68 decks
47%synergy
Myr Convert
41%inclusion28 decks68 decks
40%synergy
Gulping Scraptrap
41%inclusion28 decks68 decks
41%synergy
Toxic Nim
38%inclusion26 decks68 decks
38%synergy
Phyrexian Juggernaut
35%inclusion24 decks68 decks
35%synergy
Leaden Myr
34%inclusion23 decks68 decks
28%synergy
Defiler of Flesh
31%inclusion21 decks68 decks
27%synergy
Sheoldred's Headcleaver
28%inclusion19 decks68 decks
28%synergy
Phyrexian Crusader
25%inclusion17 decks68 decks
24%synergy
Feral Deathgorger
22%inclusion4 decks18 decks
22%synergy
Vector Asp
22%inclusion15 decks68 decks
22%synergy
Gray Merchant of Asphodel
22%inclusion15 decks68 decks
-30%synergy
Solemn Simulacrum
21%inclusion14 decks68 decks
-2%synergy
Phyrexian Digester
19%inclusion13 decks68 decks
19%synergy
Nimraiser Paladin
19%inclusion13 decks68 decks
19%synergy
Scourge Servant
18%inclusion12 decks68 decks
18%synergy
Phyrexian Vatmother
18%inclusion12 decks68 decks
18%synergy
Paragon of Open Graves
16%inclusion11 decks68 decks
15%synergy
Burnished Hart
16%inclusion11 decks68 decks
8%synergy
Swamp Mosquito
15%inclusion10 decks68 decks
15%synergy
Crypt Ghast
15%inclusion10 decks68 decks
-34%synergy
Dune Mover
13%inclusion9 decks68 decks
13%synergy
Stinging Hivemaster
13%inclusion9 decks68 decks
13%synergy
K'rrik, Son of Yawgmoth
13%inclusion9 decks68 decks
-6%synergy
Bonepicker Skirge
12%inclusion8 decks68 decks
12%synergy
Scavenger Regent
11%inclusion2 decks18 decks
10%synergy
Grafted Butcher
10%inclusion7 decks68 decks
10%synergy
Swarm, Being of Bees
10%inclusion1 decks10 decks
10%synergy
Venomized Cat
10%inclusion1 decks10 decks
10%synergy
Common Crook
10%inclusion1 decks10 decks
9%synergy
Spider-Slayer, Hatred Honed
10%inclusion1 decks10 decks
10%synergy
Plaguecrafter
8.8%inclusion6 decks68 decks
-11%synergy
Pestilent Souleater
8.8%inclusion6 decks68 decks
9%synergy
Virulent Silencer
8.3%inclusion1 decks12 decks
8%synergy
Hullcarver
8.3%inclusion1 decks12 decks
7%synergy
Spider-Man Noir
8.3%inclusion1 decks12 decks
8%synergy
Venom, Evil Unleashed
8.3%inclusion1 decks12 decks
8%synergy
Tombstone, Career Criminal
8.3%inclusion1 decks12 decks
8%synergy
Symbiote Spawn
8.3%inclusion1 decks12 decks
8%synergy
Venom, Eddie Brock
8.3%inclusion1 decks12 decks
8%synergy
Grendel, Spawn of Knull
8.3%inclusion1 decks12 decks
8%synergy
Mechanical Mobster
8.3%inclusion1 decks12 decks
8%synergy
Merciless Enforcers
8.3%inclusion1 decks12 decks
8%synergy
Scorpion, Seething Striker
8.3%inclusion1 decks12 decks
8%synergy
Spider-Bot
8.3%inclusion1 decks12 decks
8%synergy
Elephant-Rat
8.3%inclusion1 decks12 decks
8%synergy
Instants
Grim Affliction
59%inclusion40 decks68 decks
57%synergy
Whisper of the Dross
56%inclusion38 decks68 decks
53%synergy
Dark Ritual
50%inclusion34 decks68 decks
-17%synergy
Go for the Throat
49%inclusion33 decks68 decks
25%synergy
Defile
49%inclusion33 decks68 decks
11%synergy
Supernatural Stamina
44%inclusion30 decks68 decks
37%synergy
Sugar Rush
43%inclusion29 decks68 decks
42%synergy
Doom Blade
43%inclusion29 decks68 decks
35%synergy
Virulent Wound
41%inclusion28 decks68 decks
41%synergy
Consuming Corruption
33%inclusion16 decks49 decks
17%synergy
Infernal Grasp
32%inclusion22 decks68 decks
7%synergy
Tainted Strike
22%inclusion15 decks68 decks
19%synergy
Unlikely Aid
22%inclusion15 decks68 decks
21%synergy
Murder
22%inclusion15 decks68 decks
12%synergy
Astarion's Thirst
21%inclusion14 decks68 decks
19%synergy
Hero's Downfall
19%inclusion13 decks68 decks
12%synergy
Undying Malice
16%inclusion11 decks68 decks
7%synergy
Withering Torment
15%inclusion6 decks39 decks
-16%synergy
Anoint with Affliction
13%inclusion9 decks68 decks
13%synergy
Blood Pact
13%inclusion9 decks68 decks
9%synergy
Rush of Vitality
12%inclusion8 decks68 decks
11%synergy
Unnatural Endurance
12%inclusion8 decks68 decks
11%synergy
Sudden Spoiling
10%inclusion7 decks68 decks
1%synergy
Grotesque Mutation
8.8%inclusion6 decks68 decks
9%synergy
Not Dead After All
8.8%inclusion6 decks68 decks
-3%synergy
Undying Evil
8.8%inclusion6 decks68 decks
6%synergy
Fake Your Own Death
8.8%inclusion6 decks68 decks
2%synergy
Offer Immortality
8.8%inclusion6 decks68 decks
7%synergy
Scorpion's Sting
8.3%inclusion1 decks12 decks
8%synergy
Fight On!
7.7%inclusion1 decks13 decks
5%synergy
Vincent's Limit Break
7.7%inclusion1 decks13 decks
5%synergy
Imp's Mischief
7.4%inclusion5 decks68 decks
-17%synergy
Dismember
7.4%inclusion5 decks68 decks
-3%synergy
Professor's Warning
7.4%inclusion5 decks68 decks
6%synergy
Overkill
7.1%inclusion1 decks14 decks
0%synergy
Fell the Profane
6.0%inclusion3 decks50 decks
-13%synergy
Deadly Dispute
5.9%inclusion4 decks68 decks
-19%synergy
Village Rites
5.9%inclusion4 decks68 decks
-19%synergy
Bitter Triumph
5.9%inclusion4 decks68 decks
-4%synergy
Virulent Swipe
5.9%inclusion4 decks68 decks
6%synergy
Grasp of Darkness
5.9%inclusion4 decks68 decks
4%synergy
Armor of Shadows
5.9%inclusion4 decks68 decks
4%synergy
Dragon's Prey
5.6%inclusion1 decks18 decks
5%synergy
Desperate Measures
5.6%inclusion1 decks18 decks
5%synergy
Sorceries
Caress of Phyrexia
59%inclusion40 decks68 decks
58%synergy
Feed the Swarm
51%inclusion35 decks68 decks
0%synergy
Read the Bones
46%inclusion31 decks68 decks
28%synergy
Vat Emergence
43%inclusion29 decks68 decks
41%synergy
Spread the Sickness
43%inclusion29 decks68 decks
42%synergy
Phyresis Outbreak
35%inclusion24 decks68 decks
33%synergy
Night's Whisper
28%inclusion19 decks68 decks
4%synergy
Diabolic Tutor
26%inclusion18 decks68 decks
12%synergy
Mutilate
25%inclusion17 decks68 decks
7%synergy
Feed the Infection
21%inclusion14 decks68 decks
20%synergy
Crux of Fate
21%inclusion14 decks68 decks
19%synergy
Fell
16%inclusion7 decks44 decks
12%synergy
Strategic Betrayal
16%inclusion3 decks19 decks
15%synergy
Duress
15%inclusion10 decks68 decks
8%synergy
Ancient Craving
15%inclusion10 decks68 decks
12%synergy
Ambition's Cost
15%inclusion10 decks68 decks
12%synergy
Geth's Summons
13%inclusion9 decks68 decks
13%synergy
Languish
12%inclusion8 decks68 decks
10%synergy
Aggressive Negotiations
11%inclusion2 decks18 decks
11%synergy
Black Sun's Zenith
10%inclusion7 decks68 decks
4%synergy
Bubbling Muck
10%inclusion7 decks68 decks
-5%synergy
In Garruk's Wake
10%inclusion7 decks68 decks
6%synergy
Prison Break
10%inclusion1 decks10 decks
10%synergy
Risky Research
8.3%inclusion1 decks12 decks
7%synergy
Lethal Protection
8.3%inclusion1 decks12 decks
8%synergy
Venom's Hunger
8.3%inclusion1 decks12 decks
8%synergy
Cornered by Black Mages
7.7%inclusion1 decks13 decks
6%synergy
Resentful Revelation
7.7%inclusion1 decks13 decks
5%synergy
Syphon Mind
7.4%inclusion5 decks68 decks
-5%synergy
Bloodcurdling Scream
5.9%inclusion4 decks68 decks
6%synergy
Corrupt
5.9%inclusion4 decks68 decks
3%synergy
Exsanguinate
5.9%inclusion4 decks68 decks
-19%synergy
Decree of Pain
5.9%inclusion4 decks68 decks
0%synergy
Utility Artifacts
Contagion Clasp
56%inclusion38 decks68 decks
53%synergy
Blackblade Reforged
51%inclusion35 decks68 decks
49%synergy
Swiftfoot Boots
50%inclusion34 decks68 decks
18%synergy
Nightmare Lash
49%inclusion33 decks68 decks
46%synergy
Whispersilk Cloak
40%inclusion27 decks68 decks
34%synergy
Hero's Blade
40%inclusion27 decks68 decks
39%synergy
Throne of Geth
24%inclusion16 decks68 decks
23%synergy
Leyline Axe
21%inclusion7 decks34 decks
20%synergy
Inquisitor's Flail
21%inclusion14 decks68 decks
20%synergy
Bloodthorn Flail
19%inclusion13 decks68 decks
19%synergy
Wayfarer's Bauble
19%inclusion13 decks68 decks
3%synergy
Strata Scythe
19%inclusion13 decks68 decks
18%synergy
Trailblazer's Boots
18%inclusion12 decks68 decks
15%synergy
Cranial Plating
16%inclusion11 decks68 decks
13%synergy
Grafted Wargear
16%inclusion11 decks68 decks
16%synergy
Contagion Engine
15%inclusion10 decks68 decks
13%synergy
Decimator Web
15%inclusion10 decks68 decks
15%synergy
Black Mage's Rod
13%inclusion2 decks15 decks
12%synergy
Lightning Greaves
13%inclusion9 decks68 decks
-20%synergy
Livewire Lash
13%inclusion9 decks68 decks
13%synergy
Pact Weapon
13%inclusion9 decks68 decks
11%synergy
Jet Medallion
13%inclusion9 decks68 decks
-48%synergy
Loxodon Warhammer
13%inclusion9 decks68 decks
12%synergy
Grafted Exoskeleton
13%inclusion9 decks68 decks
12%synergy
Prowler's Helm
12%inclusion8 decks68 decks
11%synergy
O-Naginata
10%inclusion7 decks68 decks
10%synergy
Bladed Battle-Fan
10%inclusion7 decks68 decks
10%synergy
Doc Ock's Tentacles
10%inclusion1 decks10 decks
10%synergy
Hot Dog Cart
10%inclusion1 decks10 decks
10%synergy
Champion's Helm
8.8%inclusion6 decks68 decks
7%synergy
Prosthetic Injector
8.8%inclusion6 decks68 decks
9%synergy
Sword of Vengeance
8.8%inclusion6 decks68 decks
8%synergy
Monk's Fist
7.7%inclusion1 decks13 decks
8%synergy
Vorpal Sword
7.4%inclusion5 decks68 decks
3%synergy
Key to the City
7.4%inclusion5 decks68 decks
6%synergy
Haunted Cloak
7.4%inclusion5 decks68 decks
7%synergy
Brotherhood Regalia
6.5%inclusion3 decks46 decks
4%synergy
Quick-Draw Katana
6.1%inclusion2 decks33 decks
6%synergy
Armillary Sphere
5.9%inclusion4 decks68 decks
5%synergy
Bonesplitter
5.9%inclusion4 decks68 decks
6%synergy
Basilisk Collar
5.9%inclusion4 decks68 decks
3%synergy
Dragonfire Blade
5.6%inclusion1 decks18 decks
5%synergy
Enchantments
Necrogen Communion
53%inclusion36 decks68 decks
51%synergy
Relic Putrescence
40%inclusion27 decks68 decks
39%synergy
Fungal Fortitude
34%inclusion23 decks68 decks
32%synergy
Kaya's Ghostform
31%inclusion21 decks68 decks
21%synergy
Endless Scream
29%inclusion20 decks68 decks
29%synergy
Phyrexian Arena
25%inclusion17 decks68 decks
-15%synergy
Bad Moon
25%inclusion17 decks68 decks
22%synergy
Unspeakable Symbol
22%inclusion15 decks68 decks
21%synergy
Demonic Vigor
15%inclusion10 decks68 decks
14%synergy
Phyresis
13%inclusion9 decks68 decks
11%synergy
Snake Cult Initiation
13%inclusion9 decks68 decks
13%synergy
Shade's Form
12%inclusion8 decks68 decks
11%synergy
Alien Symbiosis
10%inclusion1 decks10 decks
10%synergy
Demonic Embrace
8.8%inclusion6 decks68 decks
8%synergy
Unholy Strength
7.4%inclusion5 decks68 decks
7%synergy
Underworld Connections
7.4%inclusion5 decks68 decks
5%synergy
Corpses of the Lost
5.9%inclusion4 decks68 decks
5%synergy
Midnight Covenant
5.9%inclusion4 decks68 decks
6%synergy
Corroding Dragonstorm
5.3%inclusion1 decks19 decks
5%synergy
Planeswalkers
Vraska, Betrayal's Sting
10%inclusion7 decks68 decks
7%synergy
Utility Lands
Rogue's Passage
59%inclusion40 decks68 decks
40%synergy
Karn's Bastion
41%inclusion28 decks68 decks
37%synergy
Bojuka Bog
28%inclusion19 decks68 decks
-19%synergy
Barren Moor
19%inclusion13 decks68 decks
9%synergy
Mortuary Mire
19%inclusion13 decks68 decks
6%synergy
Witch's Cottage
18%inclusion12 decks68 decks
-7%synergy
Temple of the False God
15%inclusion10 decks68 decks
7%synergy
Cathedral of War
13%inclusion9 decks68 decks
13%synergy
Polluted Mire
10%inclusion7 decks68 decks
6%synergy
Buried Ruin
7.4%inclusion5 decks68 decks
2%synergy
Adventurer's Inn
6.7%inclusion1 decks15 decks
5%synergy
Inkmoth Nexus
5.9%inclusion4 decks68 decks
5%synergy
Forge of Heroes
5.9%inclusion4 decks68 decks
5%synergy
Spawning Pool
5.9%inclusion4 decks68 decks
5%synergy
Great Arashin City
5.3%inclusion1 decks19 decks
5%synergy
Mana Artifacts
Sol Ring
76%inclusion52 decks68 decks
-10%synergy
Arcane Signet
60%inclusion41 decks68 decks
-2%synergy
Charcoal Diamond
57%inclusion39 decks68 decks
34%synergy
Mind Stone
46%inclusion31 decks68 decks
15%synergy
Heraldic Banner
41%inclusion28 decks68 decks
36%synergy
Commander's Sphere
25%inclusion17 decks68 decks
16%synergy
Everflowing Chalice
18%inclusion12 decks68 decks
12%synergy
Thought Vessel
15%inclusion10 decks68 decks
-12%synergy
Worn Powerstone
15%inclusion10 decks68 decks
10%synergy
Caged Sun
10%inclusion7 decks68 decks
-2%synergy
Hedron Archive
10%inclusion7 decks68 decks
7%synergy
Fellwar Stone
10%inclusion7 decks68 decks
-4%synergy
Phyrexian Atlas
8.8%inclusion6 decks68 decks
8%synergy
Staff of Compleation
5.9%inclusion4 decks68 decks
4%synergy
Glistening Sphere
5.9%inclusion4 decks68 decks
5%synergy
Thran Dynamo
5.9%inclusion4 decks68 decks
0%synergy
Darksteel Ingot
5.9%inclusion4 decks68 decks
5%synergy
Dragonstorm Globe
5.6%inclusion1 decks18 decks
6%synergy
Lands
Swamp
100%inclusion68 decks68 decks
5%synergy
Myriad Landscape
32%inclusion22 decks68 decks
6%synergy
Opal Palace
18%inclusion12 decks68 decks
17%synergy
The Seedcore
13%inclusion9 decks68 decks
13%synergy
Mirrex
8.8%inclusion6 decks68 decks
8%synergy
Evolving Wilds
8.8%inclusion6 decks68 decks
5%synergy
Terramorphic Expanse
7.4%inclusion5 decks68 decks
5%synergy
Fell the Profane
6.0%inclusion3 decks50 decks
-13%synergy
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