Skithiryx, the Blight Dragon (Commander) - Expensive Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
68decks
As CommanderAs CardAverage DeckDecks
Bracket
All12345
Budget
Any$$$$
Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
Deck Filters
Cardsphere
Archidekt
Commander Spellbook
Moxfield
Scryfall
New Cards
High Synergy Cards
Top Cards
Game Changers
Creatures
Instants
Sorceries
Utility Artifacts
Enchantments
Planeswalkers
Utility Lands
Mana Artifacts
Lands
Back to Top
Bitterbloom Bearer
10%inclusion1 decks10 decks
6%synergy
High Synergy Cards
Plague Stinger
76%inclusion52 decks68 decks
75%synergy
Plague Myr
76%inclusion52 decks68 decks
75%synergy
Phyrexian Crusader
74%inclusion50 decks68 decks
73%synergy
Inkmoth Nexus
74%inclusion50 decks68 decks
73%synergy
Ichor Rats
75%inclusion51 decks68 decks
72%synergy
Shizo, Death's Storehouse
81%inclusion55 decks68 decks
71%synergy
Infectious Inquiry
72%inclusion49 decks68 decks
69%synergy
Commander's Plate
72%inclusion49 decks68 decks
66%synergy
Whispering Specter
66%inclusion45 decks68 decks
65%synergy
Phyresis Outbreak
66%inclusion45 decks68 decks
64%synergy
Top Cards
Dark Ritual
94%inclusion64 decks68 decks
28%synergy
Jet Medallion
79%inclusion54 decks68 decks
19%synergy
Deadly Rollick
78%inclusion53 decks68 decks
54%synergy
Toxic Deluge
74%inclusion50 decks68 decks
36%synergy
Lightning Greaves
68%inclusion46 decks68 decks
34%synergy
Cabal Ritual
65%inclusion44 decks68 decks
47%synergy
Hand of the Praetors
63%inclusion43 decks68 decks
62%synergy
Vraska's Fall
62%inclusion42 decks68 decks
58%synergy
Shadowspear
62%inclusion42 decks68 decks
58%synergy
Unspeakable Symbol
62%inclusion42 decks68 decks
61%synergy
Game Changers
Ancient Tomb
93%inclusion63 decks68 decks
81%synergy
Demonic Tutor
88%inclusion60 decks68 decks
61%synergy
Vampiric Tutor
85%inclusion58 decks68 decks
64%synergy
Mana Vault
81%inclusion55 decks68 decks
74%synergy
Chrome Mox
79%inclusion54 decks68 decks
73%synergy
Necropotence
62%inclusion42 decks68 decks
47%synergy
Mox Diamond
56%inclusion38 decks68 decks
52%synergy
The One Ring
54%inclusion37 decks68 decks
45%synergy
Opposition Agent
49%inclusion33 decks68 decks
39%synergy
Imperial Seal
44%inclusion30 decks68 decks
37%synergy
Creatures
Crypt Ghast
54%inclusion37 decks68 decks
6%synergy
Blightbelly Rat
46%inclusion31 decks68 decks
42%synergy
K'rrik, Son of Yawgmoth
46%inclusion31 decks68 decks
27%synergy
Dauthi Voidwalker
46%inclusion31 decks68 decks
30%synergy
Orcish Bowmasters
38%inclusion26 decks68 decks
25%synergy
Dark Confidant
37%inclusion25 decks68 decks
30%synergy
Yawgmoth, Thran Physician
32%inclusion22 decks68 decks
22%synergy
Bilious Skulldweller
28%inclusion19 decks68 decks
27%synergy
Myr Convert
26%inclusion18 decks68 decks
26%synergy
Ichorclaw Myr
25%inclusion17 decks68 decks
24%synergy
Sheoldred, the Apocalypse
24%inclusion16 decks68 decks
9%synergy
Flensermite
22%inclusion15 decks68 decks
22%synergy
Reaper of Sheoldred
18%inclusion12 decks68 decks
17%synergy
Necropede
18%inclusion12 decks68 decks
17%synergy
Blightsteel Colossus
18%inclusion12 decks68 decks
17%synergy
Pestilent Syphoner
16%inclusion11 decks68 decks
16%synergy
Corpse Cur
16%inclusion11 decks68 decks
16%synergy
Flesh-Eater Imp
16%inclusion11 decks68 decks
15%synergy
Phyrexian Obliterator
15%inclusion10 decks68 decks
4%synergy
Gray Merchant of Asphodel
15%inclusion10 decks68 decks
-37%synergy
Massacre Girl, Known Killer
15%inclusion10 decks68 decks
11%synergy
Surge Conductor
14%inclusion2 decks14 decks
14%synergy
Core Prowler
13%inclusion9 decks68 decks
13%synergy
Septic Rats
13%inclusion9 decks68 decks
11%synergy
Phyrexian Vatmother
13%inclusion9 decks68 decks
13%synergy
Agent Venom
9.1%inclusion1 decks11 decks
7%synergy
Defiler of Flesh
8.8%inclusion6 decks68 decks
5%synergy
Filth
8.8%inclusion6 decks68 decks
6%synergy
Maha, Its Feathers Night
8.0%inclusion4 decks50 decks
3%synergy
Magus of the Coffers
7.4%inclusion5 decks68 decks
0%synergy
Witch-king of Angmar
7.4%inclusion5 decks68 decks
6%synergy
Grafted Butcher
7.4%inclusion5 decks68 decks
7%synergy
Leaden Myr
7.4%inclusion5 decks68 decks
1%synergy
Unstoppable Slasher
6.7%inclusion3 decks45 decks
1%synergy
Solemn Simulacrum
5.9%inclusion4 decks68 decks
-17%synergy
Murderous Rider
5.9%inclusion4 decks68 decks
-1%synergy
Swamp Mosquito
5.9%inclusion4 decks68 decks
6%synergy
Necroskitter
5.9%inclusion4 decks68 decks
3%synergy
Mikaeus, the Unhallowed
5.9%inclusion4 decks68 decks
-2%synergy
Nirkana Revenant
5.9%inclusion4 decks68 decks
-6%synergy
Nazgûl
5.9%inclusion4 decks68 decks
5%synergy
Phyrexian Digester
5.9%inclusion4 decks68 decks
6%synergy
Blood Pet
5.9%inclusion4 decks68 decks
-2%synergy
Bloodthirsty Conqueror
5.9%inclusion2 decks34 decks
-3%synergy
Instants
Hatred
50%inclusion34 decks68 decks
49%synergy
Imp's Mischief
50%inclusion34 decks68 decks
26%synergy
Snuff Out
50%inclusion34 decks68 decks
37%synergy
Tainted Strike
50%inclusion34 decks68 decks
47%synergy
Dismember
46%inclusion31 decks68 decks
35%synergy
Howl from Beyond
41%inclusion28 decks68 decks
40%synergy
Malakir Rebirth
29%inclusion20 decks68 decks
7%synergy
Withering Torment
29%inclusion13 decks45 decks
-3%synergy
Go for the Throat
28%inclusion19 decks68 decks
5%synergy
Defile
22%inclusion15 decks68 decks
-15%synergy
Whisper of the Dross
22%inclusion15 decks68 decks
19%synergy
Culling the Weak
22%inclusion15 decks68 decks
7%synergy
Withering Boon
22%inclusion15 decks68 decks
18%synergy
Baleful Mastery
22%inclusion15 decks68 decks
13%synergy
Archenemy's Charm
21%inclusion3 decks14 decks
13%synergy
Infernal Grasp
21%inclusion14 decks68 decks
-5%synergy
Sudden Spoiling
21%inclusion14 decks68 decks
11%synergy
Force of Despair
19%inclusion13 decks68 decks
11%synergy
Fell the Profane
16%inclusion9 decks55 decks
-2%synergy
Cut Down
16%inclusion11 decks68 decks
12%synergy
Bitter Triumph
15%inclusion10 decks68 decks
5%synergy
Slaughter Pact
15%inclusion10 decks68 decks
12%synergy
Hero's Downfall
13%inclusion9 decks68 decks
6%synergy
Darkness
13%inclusion9 decks68 decks
4%synergy
Astarion's Thirst
12%inclusion8 decks68 decks
10%synergy
Ad Nauseam
10%inclusion7 decks68 decks
8%synergy
Consuming Corruption
9.1%inclusion5 decks55 decks
-7%synergy
Blood Pact
8.8%inclusion6 decks68 decks
5%synergy
Not Dead After All
7.4%inclusion5 decks68 decks
-4%synergy
Overkill
6.7%inclusion1 decks15 decks
-1%synergy
Sheoldred's Edict
5.9%inclusion4 decks68 decks
-9%synergy
Entomb
5.9%inclusion4 decks68 decks
-6%synergy
Anoint with Affliction
5.9%inclusion4 decks68 decks
5%synergy
Grim Affliction
5.9%inclusion4 decks68 decks
4%synergy
Sugar Rush
5.9%inclusion4 decks68 decks
5%synergy
Supernatural Stamina
5.9%inclusion4 decks68 decks
-2%synergy
Tragic Slip
5.9%inclusion4 decks68 decks
-15%synergy
Rain of Filth
5.9%inclusion4 decks68 decks
3%synergy
Sorceries
Feed the Swarm
62%inclusion42 decks68 decks
11%synergy
Night's Whisper
56%inclusion38 decks68 decks
31%synergy
Crux of Fate
51%inclusion35 decks68 decks
50%synergy
Drown in Ichor
51%inclusion35 decks68 decks
47%synergy
Sign in Blood
50%inclusion34 decks68 decks
14%synergy
Bubbling Muck
49%inclusion33 decks68 decks
33%synergy
Damnation
41%inclusion28 decks68 decks
20%synergy
Insatiable Avarice
34%inclusion20 decks59 decks
22%synergy
Grim Tutor
29%inclusion20 decks68 decks
18%synergy
Reanimate
26%inclusion18 decks68 decks
-13%synergy
Praetor's Grasp
22%inclusion15 decks68 decks
18%synergy
Beseech the Mirror
16%inclusion11 decks68 decks
9%synergy
Caress of Phyrexia
16%inclusion11 decks68 decks
16%synergy
Blasphemous Edict
15%inclusion5 decks33 decks
-2%synergy
Yawgmoth's Will
13%inclusion9 decks68 decks
10%synergy
Read the Bones
12%inclusion8 decks68 decks
-6%synergy
Black Sun's Zenith
10%inclusion7 decks68 decks
4%synergy
Torment of Hailfire
10%inclusion7 decks68 decks
-5%synergy
Exsanguinate
7.4%inclusion5 decks68 decks
-17%synergy
Beseech the Queen
7.4%inclusion5 decks68 decks
1%synergy
Diabolic Tutor
5.9%inclusion4 decks68 decks
-9%synergy
Peer into the Abyss
5.9%inclusion4 decks68 decks
-5%synergy
Agadeem's Awakening
5.9%inclusion4 decks68 decks
-1%synergy
Dark Petition
5.9%inclusion4 decks68 decks
2%synergy
Thoughtseize
5.9%inclusion4 decks68 decks
1%synergy
Rush of Dread
5.1%inclusion3 decks59 decks
2%synergy
Utility Artifacts
Swiftfoot Boots
57%inclusion39 decks68 decks
26%synergy
Sword of Truth and Justice
51%inclusion35 decks68 decks
51%synergy
Lashwrithe
47%inclusion32 decks68 decks
43%synergy
Nightmare Lash
47%inclusion32 decks68 decks
45%synergy
Blackblade Reforged
41%inclusion28 decks68 decks
38%synergy
Sensei's Divining Top
38%inclusion26 decks68 decks
30%synergy
Bolas's Citadel
32%inclusion22 decks68 decks
3%synergy
Cranial Plating
32%inclusion22 decks68 decks
29%synergy
Mithril Coat
31%inclusion21 decks68 decks
25%synergy
Genji Glove
27%inclusion4 decks15 decks
26%synergy
Whispersilk Cloak
24%inclusion16 decks68 decks
18%synergy
The Darkness Crystal
24%inclusion4 decks17 decks
4%synergy
Sword of Feast and Famine
22%inclusion15 decks68 decks
20%synergy
Doc Ock's Tentacles
20%inclusion2 decks10 decks
20%synergy
Champion's Helm
19%inclusion13 decks68 decks
17%synergy
Fireshrieker
18%inclusion12 decks68 decks
16%synergy
Leyline Axe
18%inclusion6 decks34 decks
17%synergy
Black Mage's Rod
18%inclusion3 decks17 decks
17%synergy
Pip-Boy 3000
17%inclusion11 decks66 decks
16%synergy
Umezawa's Jitte
16%inclusion11 decks68 decks
16%synergy
Contagion Engine
16%inclusion11 decks68 decks
14%synergy
Wishclaw Talisman
16%inclusion11 decks68 decks
9%synergy
Pact Weapon
16%inclusion11 decks68 decks
14%synergy
Brotherhood Regalia
15%inclusion8 decks52 decks
13%synergy
Hammer of Nazahn
15%inclusion10 decks68 decks
14%synergy
Manifold Key
13%inclusion9 decks68 decks
11%synergy
Sword of Wealth and Power
12%inclusion8 decks66 decks
11%synergy
Contagion Clasp
12%inclusion8 decks68 decks
9%synergy
Expedition Map
12%inclusion8 decks68 decks
-1%synergy
Aetherflux Reservoir
12%inclusion8 decks68 decks
2%synergy
Sword of the Animist
12%inclusion8 decks68 decks
8%synergy
Hero's Blade
10%inclusion7 decks68 decks
10%synergy
Throne of Geth
8.8%inclusion6 decks68 decks
9%synergy
Trailblazer's Boots
8.8%inclusion6 decks68 decks
7%synergy
Conqueror's Flail
8.8%inclusion6 decks68 decks
8%synergy
Lavaspur Boots
8.3%inclusion5 decks60 decks
7%synergy
Helm of Obedience
7.4%inclusion5 decks68 decks
7%synergy
O-Naginata
7.4%inclusion5 decks68 decks
7%synergy
Sword of Fire and Ice
7.4%inclusion5 decks68 decks
7%synergy
Thran Power Suit
7.4%inclusion5 decks68 decks
7%synergy
Grafted Wargear
7.4%inclusion5 decks68 decks
7%synergy
Dark Knight's Greatsword
6.7%inclusion1 decks15 decks
6%synergy
Buster Sword
6.3%inclusion1 decks16 decks
5%synergy
Aettir and Priwen
6.3%inclusion1 decks16 decks
6%synergy
Silver Shroud Costume
6.1%inclusion4 decks66 decks
5%synergy
Radiant Lotus
5.9%inclusion1 decks17 decks
6%synergy
Bontu's Monument
5.9%inclusion4 decks68 decks
-22%synergy
Mindcrank
5.9%inclusion4 decks68 decks
0%synergy
Bloodforged Battle-Axe
5.9%inclusion4 decks68 decks
6%synergy
Sword of Sinew and Steel
5.9%inclusion4 decks68 decks
6%synergy
Enchantments
Black Market Connections
53%inclusion36 decks68 decks
30%synergy
Phyrexian Arena
53%inclusion36 decks68 decks
13%synergy
Necrogen Communion
35%inclusion24 decks68 decks
33%synergy
Super State
21%inclusion3 decks14 decks
21%synergy
The Meathook Massacre
21%inclusion14 decks68 decks
3%synergy
Kaya's Ghostform
18%inclusion12 decks68 decks
7%synergy
Animate Dead
15%inclusion10 decks68 decks
-3%synergy
Contamination
13%inclusion9 decks68 decks
10%synergy
Phyresis
13%inclusion9 decks68 decks
11%synergy
No Mercy
12%inclusion8 decks68 decks
5%synergy
Bitterblossom
12%inclusion8 decks68 decks
-1%synergy
Endless Scream
10%inclusion7 decks68 decks
10%synergy
Leyline of the Void
10%inclusion7 decks68 decks
8%synergy
Phyrexian Reclamation
8.8%inclusion6 decks68 decks
-1%synergy
Bloodchief Ascension
8.8%inclusion6 decks68 decks
-1%synergy
Oubliette
8.8%inclusion6 decks68 decks
6%synergy
Shade's Form
7.4%inclusion5 decks68 decks
7%synergy
Heartless Summoning
7.4%inclusion5 decks68 decks
3%synergy
Bad Moon
7.4%inclusion5 decks68 decks
4%synergy
Call of the Ring
5.9%inclusion4 decks68 decks
3%synergy
Dauthi Embrace
5.9%inclusion4 decks68 decks
4%synergy
Planeswalkers
Vraska, Betrayal's Sting
50%inclusion34 decks68 decks
47%synergy
Liliana of the Dark Realms
35%inclusion24 decks68 decks
21%synergy
Tezzeret, Cruel Captain
14%inclusion2 decks14 decks
13%synergy
Utility Lands
Urborg, Tomb of Yawgmoth
87%inclusion59 decks68 decks
49%synergy
Cabal Coffers
85%inclusion58 decks68 decks
30%synergy
Karn's Bastion
63%inclusion43 decks68 decks
59%synergy
Rogue's Passage
60%inclusion41 decks68 decks
42%synergy
Urza's Saga
51%inclusion35 decks68 decks
43%synergy
Lake of the Dead
44%inclusion30 decks68 decks
39%synergy
The Black Gate
35%inclusion24 decks68 decks
32%synergy
Nykthos, Shrine to Nyx
34%inclusion23 decks68 decks
4%synergy
Bojuka Bog
32%inclusion22 decks68 decks
-15%synergy
Strip Mine
32%inclusion22 decks68 decks
29%synergy
Cabal Stronghold
24%inclusion16 decks68 decks
-12%synergy
Command Beacon
24%inclusion16 decks68 decks
15%synergy
Minas Morgul, Dark Fortress
22%inclusion15 decks68 decks
19%synergy
Vault of Whispers
21%inclusion14 decks68 decks
15%synergy
Takenuma, Abandoned Mire
21%inclusion14 decks68 decks
5%synergy
Castle Locthwain
21%inclusion14 decks68 decks
3%synergy
Volrath's Stronghold
16%inclusion11 decks68 decks
12%synergy
Homeward Path
16%inclusion11 decks68 decks
14%synergy
Phyrexian Tower
13%inclusion9 decks68 decks
-11%synergy
Cathedral of War
13%inclusion9 decks68 decks
13%synergy
City of Traitors
12%inclusion8 decks68 decks
10%synergy
Wasteland
10%inclusion7 decks68 decks
9%synergy
War Room
10%inclusion7 decks68 decks
-6%synergy
Reliquary Tower
10%inclusion7 decks68 decks
-21%synergy
Deserted Temple
8.8%inclusion6 decks68 decks
5%synergy
Maze of Ith
7.4%inclusion5 decks68 decks
4%synergy
Midgar, City of Mako
6.7%inclusion1 decks15 decks
-5%synergy
Hall of the Bandit Lord
5.9%inclusion4 decks68 decks
5%synergy
Darksteel Citadel
5.9%inclusion4 decks68 decks
5%synergy
Thespian's Stage
5.9%inclusion4 decks68 decks
0%synergy
Mishra's Workshop
5.9%inclusion4 decks68 decks
6%synergy
Dark Depths
5.9%inclusion4 decks68 decks
5%synergy
Spymaster's Vault
5.5%inclusion3 decks55 decks
-4%synergy
Mana Artifacts
Sol Ring
97%inclusion66 decks68 decks
11%synergy
Arcane Signet
82%inclusion56 decks68 decks
20%synergy
Mox Opal
74%inclusion50 decks68 decks
70%synergy
Lotus Petal
68%inclusion46 decks68 decks
60%synergy
The Soul Stone
57%inclusion8 decks14 decks
44%synergy
Glistening Sphere
43%inclusion29 decks68 decks
41%synergy
Grim Monolith
38%inclusion26 decks68 decks
35%synergy
Staff of Compleation
37%inclusion25 decks68 decks
35%synergy
Mana Crypt
32%inclusion22 decks68 decks
30%synergy
Jeweled Lotus
31%inclusion21 decks68 decks
29%synergy
Mox Amber
28%inclusion19 decks68 decks
24%synergy
Fellwar Stone
24%inclusion16 decks68 decks
9%synergy
Throne of Eldraine
22%inclusion15 decks68 decks
12%synergy
Mind Stone
22%inclusion15 decks68 decks
-8%synergy
Mox Jasper
18%inclusion3 decks17 decks
18%synergy
Heraldic Banner
13%inclusion9 decks68 decks
8%synergy
Everflowing Chalice
12%inclusion8 decks68 decks
6%synergy
Thran Dynamo
8.8%inclusion6 decks68 decks
3%synergy
Sceptre of Eternal Glory
8.8%inclusion6 decks68 decks
0%synergy
Patchwork Banner
8.0%inclusion4 decks50 decks
4%synergy
Caged Sun
7.4%inclusion5 decks68 decks
-5%synergy
Charcoal Diamond
7.4%inclusion5 decks68 decks
-16%synergy
Thought Vessel
7.4%inclusion5 decks68 decks
-19%synergy
Mox Tantalite
7.4%inclusion5 decks68 decks
7%synergy
Extraplanar Lens
7.4%inclusion5 decks68 decks
2%synergy
Worn Powerstone
5.9%inclusion4 decks68 decks
2%synergy
Lands
Swamp
88%inclusion60 decks68 decks
-7%synergy
Cavern of Souls
72%inclusion49 decks68 decks
65%synergy
Gemstone Caverns
34%inclusion23 decks68 decks
29%synergy
Malakir Rebirth
29%inclusion20 decks68 decks
7%synergy
Verdant Catacombs
25%inclusion17 decks68 decks
22%synergy
Polluted Delta
24%inclusion16 decks68 decks
20%synergy
Bloodstained Mire
24%inclusion16 decks68 decks
20%synergy
Marsh Flats
22%inclusion15 decks68 decks
19%synergy
Fell the Profane
16%inclusion9 decks55 decks
-2%synergy
Mirrex
15%inclusion10 decks68 decks
14%synergy
Plaza of Heroes
15%inclusion10 decks68 decks
14%synergy
Snow-Covered Swamp
13%inclusion9 decks68 decks
6%synergy
Prismatic Vista
10%inclusion7 decks68 decks
8%synergy
Command Tower
10%inclusion7 decks68 decks
5%synergy
Fabled Passage
7.4%inclusion5 decks68 decks
6%synergy
The Seedcore
5.9%inclusion4 decks68 decks
6%synergy
Agadeem's Awakening
5.9%inclusion4 decks68 decks
-1%synergy
Talon Gates of Madara
5.6%inclusion3 decks54 decks
4%synergy
Urza's Cave
5.3%inclusion3 decks57 decks
-3%synergy
About UsContactPrivacy PolicyTerms of Service
Space Cow MediaArchidektCardsphereCommander SpellbookFABRECSpellvoid
Space Cow MediaArchidektCommander's Herald
Commander SpellbookFABRECSpellvoid
EDHREC is unofficial Fan Content permitted under the Fan Content Policy. Not approved/endorsed by Wizards. Portions of the materials used are property of Wizards of the Coast. ©Wizards of the Coast LLC.
next@15 test