Skithiryx, the Blight Dragon (Commander) - Expensive Optimized Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #816
2decks
As CommanderAs CardAverage DeckDecks
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1
234
5
Budget
Any$$$$
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Phyrexian Crusader
100%inclusion2 decks2 decks
2.5xlift
Phyrexian Juggernaut
50%inclusion1 decks2 decks
2.5xlift
Plague Stinger
50%inclusion1 decks2 decks
2.5xlift
Maha, Its Feathers Night
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2.5xlift
Whispering Specter
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2.5xlift
Opposition Agent
50%inclusion1 decks2 decks
2.5xlift
Dark Confidant
50%inclusion1 decks2 decks
1.3xlift
Reaper of Sheoldred
50%inclusion1 decks2 decks
2.5xlift
Sheoldred, the Apocalypse
50%inclusion1 decks2 decks
1.3xlift
Ornithopter of Paradise
50%inclusion1 decks2 decks
2.5xlift
Flensermite
50%inclusion1 decks2 decks
2.5xlift
Carnifex Demon
50%inclusion1 decks2 decks
2.5xlift
Archfiend of Ifnir
50%inclusion1 decks2 decks
2.5xlift
Necroskitter
50%inclusion1 decks2 decks
2.5xlift
Varragoth, Bloodsky Sire
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2.5xlift
Nirkana Revenant
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2.5xlift
Ichorclaw Myr
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2.5xlift
Yawgmoth, Thran Physician
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2.5xlift
Crypt Ghast
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2.5xlift
Archfiend of Depravity
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2.5xlift
Chainer, Dementia Master
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2.5xlift
Massacre Girl, Known Killer
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Soul Snuffers
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Midnight Banshee
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2.5xlift
Braids, Arisen Nightmare
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2.5xlift
Necropede
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2.5xlift
Orcish Bowmasters
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2.5xlift
Dauthi Voidwalker
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1.3xlift
Hand of the Praetors
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2.5xlift
Ichor Rats
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1.3xlift
Virulent Silencer
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2.5xlift
Instants
Deadly Rollick
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Dark Ritual
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1.0xlift
Fatal Push
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2.5xlift
Snuff Out
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1.3xlift
Vraska's Fall
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1.3xlift
Bitter Triumph
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1.3xlift
Infernal Grasp
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2.5xlift
Tainted Strike
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Black Sun's Twilight
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V.A.T.S.
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Vampiric Tutor
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Saw in Half
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Dismember
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2.5xlift
Archenemy's Charm
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Sorceries
Toxic Deluge
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1.7xlift
Pox Plague
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Black Sun's Zenith
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1.3xlift
Yawgmoth's Will
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Bubbling Muck
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2.5xlift
Phyresis Outbreak
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0.8xlift
Crux of Fate
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2.5xlift
Pox
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2.5xlift
Infectious Inquiry
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1.3xlift
Praetor's Grasp
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2.5xlift
Smallpox
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2.5xlift
Exsanguinate
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1.3xlift
Demonic Tutor
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0.6xlift
Drown in Ichor
50%inclusion1 decks2 decks
1.3xlift
Utility Artifacts
Swiftfoot Boots
100%inclusion2 decks2 decks
2.5xlift
Blackblade Reforged
100%inclusion2 decks2 decks
2.5xlift
Lashwrithe
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2.5xlift
Defense Grid
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2.5xlift
Thran Power Suit
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2.5xlift
Contagion Clasp
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2.5xlift
Contagion Engine
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2.5xlift
Leyline Axe
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2.5xlift
Scroll Rack
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2.5xlift
Skullclamp
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1.3xlift
Nim Deathmantle
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2.5xlift
Cranial Plating
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2.5xlift
Sword of Truth and Justice
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2.5xlift
Wishclaw Talisman
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2.5xlift
Sword of Hearth and Home
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2.5xlift
Conqueror's Flail
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2.5xlift
Excalibur, Sword of Eden
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2.5xlift
Fireshrieker
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Netherborn Altar
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2.5xlift
Key to the City
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2.5xlift
Sword of Wealth and Power
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2.5xlift
Resurrection Orb
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2.5xlift
Winter Moon
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2.5xlift
Champion's Helm
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2.5xlift
Lightning Greaves
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0.8xlift
Tome of Legends
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2.5xlift
Commander's Plate
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2.5xlift
Sword of Feast and Famine
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2.5xlift
Sword of the Animist
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2.5xlift
Dragonfire Blade
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2.5xlift
Adaptive Omnitool
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2.5xlift
Basilisk Collar
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2.5xlift
The Darkness Crystal
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2.5xlift
Genji Glove
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2.5xlift
Enchantments
Phyrexian Arena
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1.3xlift
Nest of Scarabs
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1.3xlift
Black Market
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2.5xlift
Eldrazi Conscription
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2.5xlift
Blowfly Infestation
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2.5xlift
Contamination
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2.5xlift
Nether Void
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2.5xlift
Soul Kiss
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2.5xlift
Necropotence
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1.3xlift
Phyresis
50%inclusion1 decks2 decks
1.3xlift
Black Market Connections
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0.8xlift
Chains of Mephistopheles
50%inclusion1 decks2 decks
2.5xlift
Oppression
50%inclusion1 decks2 decks
2.5xlift
Super State
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2.5xlift
Planeswalkers
Vraska, Betrayal's Sting
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1.7xlift
Liliana of the Dark Realms
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1.7xlift
Liliana of the Veil
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2.5xlift
Utility Lands
Ancient Tomb
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0.8xlift
The Black Gate
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2.5xlift
Urza's Saga
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2.5xlift
Inkmoth Nexus
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1.3xlift
The Tabernacle at Pendrell Vale
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2.5xlift
War Room
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2.5xlift
Cabal Coffers
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0.6xlift
Nykthos, Shrine to Nyx
50%inclusion1 decks2 decks
0.8xlift
Karn's Bastion
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0.8xlift
Takenuma, Abandoned Mire
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1.3xlift
Ifnir Deadlands
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2.5xlift
Mishra's Workshop
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2.5xlift
Urborg, Tomb of Yawgmoth
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0.6xlift
Rogue's Passage
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2.5xlift
Secluded Starforge
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2.5xlift
Mana Artifacts
Sol Ring
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1.0xlift
Wickersmith's Tools
100%inclusion1 decks1 decks
4.0xlift
Staff of Compleation
50%inclusion1 decks2 decks
2.5xlift
Lotus Petal
50%inclusion1 decks2 decks
1.3xlift
Thran Dynamo
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2.5xlift
Sonic Screwdriver
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2.5xlift
Mox Opal
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2.5xlift
Extraplanar Lens
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2.5xlift
Chrome Mox
50%inclusion1 decks2 decks
1.3xlift
Mox Diamond
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1.3xlift
Lands
Swamp
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1.0xlift
Fabled Passage
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1.3xlift
Myriad Landscape
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2.5xlift
Verdant Catacombs
50%inclusion1 decks2 decks
1.3xlift
Cavern of Souls
50%inclusion1 decks2 decks
1.3xlift
Bloodstained Mire
50%inclusion1 decks2 decks
1.3xlift
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