Skithiryx, the Blight Dragon (Commander) - Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
682decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Splinter's Technique
4.3%inclusion1 decks23 decks
4%synergy
Moonshadow
2.9%inclusion1 decks34 decks
1%synergy
Bitterbloom Bearer
2.9%inclusion3 decks102 decks
-1%synergy
Unbury
2.9%inclusion1 decks35 decks
2%synergy
Eventide's Shadow
2.8%inclusion1 decks36 decks
3%synergy
High Synergy Cards
Plague Stinger
81%inclusion550 decks682 decks
80%synergy
Plague Myr
78%inclusion535 decks682 decks
77%synergy
Hand of the Praetors
76%inclusion517 decks682 decks
75%synergy
Ichor Rats
78%inclusion533 decks682 decks
75%synergy
Infectious Inquiry
76%inclusion519 decks682 decks
73%synergy
Vraska's Fall
71%inclusion484 decks682 decks
67%synergy
Whispering Specter
67%inclusion457 decks682 decks
66%synergy
Karn's Bastion
69%inclusion469 decks682 decks
65%synergy
Phyrexian Crusader
65%inclusion445 decks682 decks
64%synergy
Drown in Ichor
66%inclusion450 decks682 decks
62%synergy
Top Cards
Dark Ritual
79%inclusion537 decks682 decks
12%synergy
Lashwrithe
64%inclusion437 decks682 decks
60%synergy
Jet Medallion
64%inclusion434 decks682 decks
3%synergy
Swiftfoot Boots
63%inclusion431 decks682 decks
32%synergy
Blightbelly Rat
61%inclusion419 decks682 decks
58%synergy
Crypt Ghast
61%inclusion417 decks682 decks
13%synergy
Phyrexian Arena
61%inclusion414 decks682 decks
21%synergy
Phyresis Outbreak
60%inclusion412 decks682 decks
59%synergy
Nightmare Lash
58%inclusion393 decks682 decks
55%synergy
Sign in Blood
57%inclusion392 decks682 decks
21%synergy
Game Changers
Demonic Tutor
42%inclusion285 decks682 decks
14%synergy
Vampiric Tutor
31%inclusion214 decks682 decks
10%synergy
Necropotence
22%inclusion149 decks682 decks
7%synergy
Ancient Tomb
21%inclusion144 decks682 decks
9%synergy
Bolas's Citadel
17%inclusion114 decks682 decks
-12%synergy
Mana Vault
15%inclusion104 decks682 decks
8%synergy
Opposition Agent
13%inclusion89 decks682 decks
3%synergy
The One Ring
11%inclusion78 decks682 decks
2%synergy
Chrome Mox
11%inclusion73 decks682 decks
5%synergy
Imperial Seal
9.4%inclusion64 decks682 decks
2%synergy
Creatures
Reaper of Sheoldred
54%inclusion366 decks682 decks
53%synergy
Ichorclaw Myr
47%inclusion318 decks682 decks
46%synergy
Flensermite
45%inclusion307 decks682 decks
45%synergy
Bilious Skulldweller
44%inclusion300 decks682 decks
43%synergy
Core Prowler
44%inclusion299 decks682 decks
43%synergy
Corpse Cur
43%inclusion290 decks682 decks
42%synergy
Pestilent Syphoner
38%inclusion260 decks682 decks
37%synergy
Flesh-Eater Imp
38%inclusion260 decks682 decks
37%synergy
Septic Rats
36%inclusion243 decks682 decks
34%synergy
Phyrexian Obliterator
35%inclusion236 decks682 decks
24%synergy
K'rrik, Son of Yawgmoth
31%inclusion211 decks682 decks
12%synergy
Necropede
28%inclusion193 decks682 decks
28%synergy
Myr Convert
27%inclusion184 decks682 decks
26%synergy
Yawgmoth, Thran Physician
24%inclusion165 decks682 decks
14%synergy
Blightsteel Colossus
22%inclusion153 decks682 decks
22%synergy
Solemn Simulacrum
22%inclusion149 decks682 decks
-1%synergy
Gray Merchant of Asphodel
22%inclusion148 decks682 decks
-30%synergy
Contagious Nim
21%inclusion141 decks682 decks
20%synergy
Leaden Myr
20%inclusion136 decks682 decks
14%synergy
Gulping Scraptrap
18%inclusion124 decks682 decks
18%synergy
Blackcleave Goblin
17%inclusion118 decks682 decks
17%synergy
Phyrexian Juggernaut
16%inclusion106 decks682 decks
15%synergy
Massacre Girl, Known Killer
15%inclusion100 decks682 decks
11%synergy
Magus of the Coffers
14%inclusion98 decks682 decks
7%synergy
Defiler of Flesh
14%inclusion96 decks682 decks
10%synergy
Necroskitter
14%inclusion95 decks682 decks
11%synergy
Dauthi Voidwalker
14%inclusion94 decks682 decks
-2%synergy
Phyrexian Vatmother
13%inclusion88 decks682 decks
13%synergy
Sheoldred, Whispering One
13%inclusion88 decks682 decks
1%synergy
Dread Presence
13%inclusion87 decks682 decks
-2%synergy
Toxic Nim
12%inclusion85 decks682 decks
12%synergy
Grafted Butcher
12%inclusion81 decks682 decks
12%synergy
Filth
11%inclusion78 decks682 decks
9%synergy
Sheoldred's Headcleaver
11%inclusion78 decks682 decks
11%synergy
Dark Confidant
11%inclusion76 decks682 decks
4%synergy
Silent Arbiter
10%inclusion67 decks682 decks
8%synergy
Nirkana Revenant
10%inclusion65 decks682 decks
-2%synergy
Phyrexian Digester
9.1%inclusion62 decks682 decks
9%synergy
Sheoldred, the Apocalypse
9.1%inclusion62 decks682 decks
-6%synergy
Burnished Hart
8.7%inclusion59 decks682 decks
1%synergy
Nimraiser Paladin
7.9%inclusion54 decks682 decks
8%synergy
Orcish Bowmasters
7.9%inclusion54 decks682 decks
-6%synergy
Vector Asp
7.8%inclusion53 decks682 decks
8%synergy
Maha, Its Feathers Night
7.8%inclusion38 decks489 decks
3%synergy
Massacre Wurm
7.2%inclusion49 decks682 decks
-10%synergy
Surge Conductor
6.7%inclusion9 decks135 decks
7%synergy
Swamp Mosquito
6.6%inclusion45 decks682 decks
6%synergy
Brass Squire
6.6%inclusion45 decks682 decks
6%synergy
Scourge Servant
6.5%inclusion44 decks682 decks
6%synergy
Gwenom, Remorseless
6.3%inclusion8 decks126 decks
3%synergy
Instants
Howl from Beyond
51%inclusion351 decks682 decks
51%synergy
Whisper of the Dross
46%inclusion317 decks682 decks
43%synergy
Defile
45%inclusion306 decks682 decks
8%synergy
Go for the Throat
40%inclusion272 decks682 decks
17%synergy
Tainted Strike
39%inclusion263 decks682 decks
35%synergy
Grim Affliction
36%inclusion246 decks682 decks
34%synergy
Deadly Rollick
32%inclusion221 decks682 decks
9%synergy
Infernal Grasp
32%inclusion220 decks682 decks
7%synergy
Withering Torment
30%inclusion122 decks411 decks
-2%synergy
Dismember
29%inclusion199 decks682 decks
18%synergy
Cabal Ritual
28%inclusion188 decks682 decks
10%synergy
Imp's Mischief
27%inclusion184 decks682 decks
3%synergy
Sugar Rush
24%inclusion165 decks682 decks
24%synergy
Supernatural Stamina
22%inclusion152 decks682 decks
15%synergy
Hatred
20%inclusion138 decks682 decks
19%synergy
Astarion's Thirst
19%inclusion128 decks682 decks
17%synergy
Virulent Wound
19%inclusion127 decks682 decks
18%synergy
Sudden Spoiling
18%inclusion122 decks682 decks
9%synergy
Malakir Rebirth
18%inclusion122 decks682 decks
-5%synergy
Consuming Corruption
17%inclusion93 decks539 decks
1%synergy
Snuff Out
17%inclusion115 decks682 decks
4%synergy
Archenemy's Charm
16%inclusion22 decks135 decks
7%synergy
Hero's Downfall
16%inclusion109 decks682 decks
9%synergy
Doom Blade
15%inclusion101 decks682 decks
7%synergy
Fell the Profane
13%inclusion73 decks545 decks
-5%synergy
Force of Despair
13%inclusion91 decks682 decks
6%synergy
Unlikely Aid
13%inclusion87 decks682 decks
12%synergy
Anoint with Affliction
12%inclusion83 decks682 decks
12%synergy
Murder
12%inclusion83 decks682 decks
2%synergy
Baleful Mastery
12%inclusion82 decks682 decks
3%synergy
Darkness
10%inclusion67 decks682 decks
0%synergy
Withering Boon
10%inclusion66 decks682 decks
5%synergy
Sheoldred's Edict
9.1%inclusion62 decks682 decks
-5%synergy
Undying Malice
8.8%inclusion60 decks682 decks
-1%synergy
Bitter Triumph
8.2%inclusion56 decks682 decks
-2%synergy
Culling the Weak
8.1%inclusion55 decks682 decks
-7%synergy
Not Dead After All
7.5%inclusion51 decks682 decks
-4%synergy
Cut Down
7.5%inclusion51 decks682 decks
3%synergy
Rush of Vitality
7.5%inclusion51 decks682 decks
7%synergy
Tragic Slip
7.0%inclusion48 decks682 decks
-13%synergy
Undying Evil
7.0%inclusion48 decks682 decks
4%synergy
Soul Shatter
6.5%inclusion44 decks682 decks
-6%synergy
Unnatural Endurance
6.3%inclusion43 decks682 decks
6%synergy
Slaughter Pact
5.7%inclusion39 decks682 decks
3%synergy
Blood Pact
5.4%inclusion37 decks682 decks
1%synergy
Overkill
5.3%inclusion8 decks151 decks
-2%synergy
Sorceries
Feed the Swarm
55%inclusion375 decks682 decks
4%synergy
Night's Whisper
48%inclusion324 decks682 decks
23%synergy
Crux of Fate
41%inclusion280 decks682 decks
40%synergy
Toxic Deluge
40%inclusion273 decks682 decks
3%synergy
Caress of Phyrexia
38%inclusion261 decks682 decks
38%synergy
Read the Bones
34%inclusion230 decks682 decks
16%synergy
Bubbling Muck
31%inclusion209 decks682 decks
15%synergy
Damnation
27%inclusion186 decks682 decks
7%synergy
Vat Emergence
24%inclusion162 decks682 decks
22%synergy
Reanimate
23%inclusion160 decks682 decks
-16%synergy
Diabolic Tutor
22%inclusion153 decks682 decks
8%synergy
Insatiable Avarice
18%inclusion114 decks624 decks
6%synergy
Spread the Sickness
18%inclusion124 decks682 decks
17%synergy
Mutilate
18%inclusion121 decks682 decks
-1%synergy
Grim Tutor
16%inclusion108 decks682 decks
4%synergy
Blasphemous Edict
13%inclusion45 decks335 decks
-4%synergy
Exsanguinate
12%inclusion85 decks682 decks
-12%synergy
Geth's Summons
12%inclusion85 decks682 decks
12%synergy
Black Sun's Zenith
11%inclusion78 decks682 decks
6%synergy
Feed the Infection
9.1%inclusion62 decks682 decks
8%synergy
Beseech the Queen
7.6%inclusion52 decks682 decks
2%synergy
Profane Tutor
7.5%inclusion51 decks682 decks
3%synergy
In Garruk's Wake
7.0%inclusion48 decks682 decks
3%synergy
Syphon Mind
7.0%inclusion48 decks682 decks
-6%synergy
Fell
6.3%inclusion31 decks489 decks
3%synergy
Torment of Hailfire
6.3%inclusion43 decks682 decks
-9%synergy
Villainous Wrath
5.3%inclusion6 decks113 decks
3%synergy
Praetor's Grasp
5.3%inclusion36 decks682 decks
1%synergy
Utility Artifacts
Blackblade Reforged
52%inclusion357 decks682 decks
49%synergy
Lightning Greaves
51%inclusion350 decks682 decks
18%synergy
Fireshrieker
46%inclusion314 decks682 decks
44%synergy
Contagion Clasp
42%inclusion289 decks682 decks
40%synergy
Whispersilk Cloak
41%inclusion281 decks682 decks
35%synergy
Contagion Engine
37%inclusion251 decks682 decks
35%synergy
Sword of Truth and Justice
37%inclusion250 decks682 decks
36%synergy
Commander's Plate
35%inclusion240 decks682 decks
30%synergy
Shadowspear
28%inclusion194 decks682 decks
25%synergy
The Darkness Crystal
24%inclusion38 decks157 decks
4%synergy
Leyline Axe
22%inclusion75 decks337 decks
21%synergy
Champion's Helm
21%inclusion140 decks682 decks
19%synergy
Hero's Blade
20%inclusion135 decks682 decks
19%synergy
Trailblazer's Boots
19%inclusion129 decks682 decks
17%synergy
Brotherhood Regalia
17%inclusion89 decks511 decks
15%synergy
Sword of the Animist
17%inclusion113 decks682 decks
13%synergy
Cranial Plating
15%inclusion101 decks682 decks
11%synergy
Mithril Coat
15%inclusion99 decks682 decks
9%synergy
Pact Weapon
15%inclusion99 decks682 decks
12%synergy
Throne of Geth
14%inclusion95 decks682 decks
14%synergy
Sword of Feast and Famine
13%inclusion92 decks682 decks
12%synergy
Expedition Map
13%inclusion91 decks682 decks
1%synergy
Genji Glove
13%inclusion20 decks150 decks
12%synergy
Wayfarer's Bauble
13%inclusion90 decks682 decks
-3%synergy
Strata Scythe
11%inclusion74 decks682 decks
10%synergy
Doc Ock's Tentacles
11%inclusion12 decks113 decks
10%synergy
Grafted Exoskeleton
11%inclusion72 decks682 decks
9%synergy
Inquisitor's Flail
10%inclusion70 decks682 decks
10%synergy
Sword of Vengeance
10%inclusion68 decks682 decks
9%synergy
Hammer of Nazahn
8.9%inclusion61 decks682 decks
8%synergy
Loxodon Warhammer
8.7%inclusion59 decks682 decks
7%synergy
Pip-Boy 3000
8.4%inclusion56 decks668 decks
8%synergy
Bontu's Monument
8.4%inclusion57 decks682 decks
-20%synergy
Prowler's Helm
8.4%inclusion57 decks682 decks
7%synergy
Helm of the Host
8.1%inclusion55 decks682 decks
7%synergy
Darksteel Plate
8.1%inclusion55 decks682 decks
6%synergy
Sensei's Divining Top
7.9%inclusion54 decks682 decks
0%synergy
Basilisk Collar
7.6%inclusion52 decks682 decks
5%synergy
Grafted Wargear
7.3%inclusion50 decks682 decks
7%synergy
Sword of Wealth and Power
7.3%inclusion49 decks669 decks
7%synergy
Vorpal Sword
7.0%inclusion48 decks682 decks
3%synergy
O-Naginata
6.5%inclusion44 decks682 decks
6%synergy
Whip of Erebos
6.2%inclusion42 decks682 decks
-5%synergy
Black Mage's Rod
5.7%inclusion9 decks157 decks
5%synergy
Manifold Key
5.4%inclusion37 decks682 decks
4%synergy
Sword of Fire and Ice
5.4%inclusion37 decks682 decks
5%synergy
Decimator Web
5.3%inclusion36 decks682 decks
5%synergy
Buster Sword
5.2%inclusion8 decks154 decks
4%synergy
Mask of Avacyn
5.1%inclusion35 decks682 decks
4%synergy
Enchantments
Necrogen Communion
50%inclusion342 decks682 decks
48%synergy
Unspeakable Symbol
39%inclusion267 decks682 decks
38%synergy
Kaya's Ghostform
29%inclusion199 decks682 decks
19%synergy
Black Market Connections
22%inclusion151 decks682 decks
-1%synergy
Bad Moon
21%inclusion142 decks682 decks
17%synergy
Fungal Fortitude
18%inclusion124 decks682 decks
17%synergy
Phyresis
16%inclusion108 decks682 decks
14%synergy
No Mercy
15%inclusion104 decks682 decks
8%synergy
Relic Putrescence
15%inclusion100 decks682 decks
14%synergy
Endless Scream
14%inclusion96 decks682 decks
14%synergy
Dauthi Embrace
11%inclusion74 decks682 decks
9%synergy
Shade's Form
11%inclusion73 decks682 decks
10%synergy
Snake Cult Initiation
7.9%inclusion54 decks682 decks
8%synergy
Animate Dead
7.3%inclusion50 decks682 decks
-10%synergy
Super State
7.3%inclusion10 decks137 decks
7%synergy
Alien Symbiosis
7.1%inclusion8 decks113 decks
7%synergy
Black Market
6.7%inclusion46 decks682 decks
-14%synergy
Greed
5.7%inclusion39 decks682 decks
-1%synergy
The Meathook Massacre
5.4%inclusion37 decks682 decks
-12%synergy
Glistening Oil
5.3%inclusion36 decks682 decks
5%synergy
Phyrexian Reclamation
5.1%inclusion35 decks682 decks
-5%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion315 decks682 decks
43%synergy
Liliana of the Dark Realms
28%inclusion193 decks682 decks
14%synergy
Utility Lands
Rogue's Passage
68%inclusion461 decks682 decks
49%synergy
Cabal Coffers
62%inclusion422 decks682 decks
7%synergy
Bojuka Bog
48%inclusion329 decks682 decks
1%synergy
Urborg, Tomb of Yawgmoth
47%inclusion321 decks682 decks
9%synergy
Shizo, Death's Storehouse
44%inclusion302 decks682 decks
34%synergy
Inkmoth Nexus
41%inclusion281 decks682 decks
40%synergy
Cabal Stronghold
38%inclusion256 decks682 decks
2%synergy
Nykthos, Shrine to Nyx
25%inclusion170 decks682 decks
-5%synergy
The Black Gate
20%inclusion135 decks682 decks
16%synergy
Cathedral of War
19%inclusion130 decks682 decks
19%synergy
Castle Locthwain
17%inclusion117 decks682 decks
0%synergy
Command Beacon
16%inclusion112 decks682 decks
8%synergy
War Room
16%inclusion109 decks682 decks
0%synergy
Reliquary Tower
15%inclusion99 decks682 decks
-17%synergy
Witch's Cottage
13%inclusion86 decks682 decks
-12%synergy
Minas Morgul, Dark Fortress
11%inclusion77 decks682 decks
8%synergy
Urza's Saga
11%inclusion76 decks682 decks
3%synergy
Mortuary Mire
9.4%inclusion64 decks682 decks
-4%synergy
Temple of the False God
9.2%inclusion63 decks682 decks
1%synergy
Lake of the Dead
8.9%inclusion61 decks682 decks
4%synergy
Strip Mine
8.7%inclusion59 decks682 decks
6%synergy
Takenuma, Abandoned Mire
8.2%inclusion56 decks682 decks
-8%synergy
Barren Moor
7.8%inclusion53 decks682 decks
-2%synergy
Maze of Ith
6.7%inclusion46 decks682 decks
3%synergy
Buried Ruin
6.2%inclusion42 decks682 decks
1%synergy
Phyrexian Tower
6.0%inclusion41 decks682 decks
-18%synergy
Thespian's Stage
5.4%inclusion37 decks682 decks
0%synergy
Spymaster's Vault
5.3%inclusion29 decks545 decks
-4%synergy
Homeward Path
5.1%inclusion35 decks682 decks
3%synergy
Mana Artifacts
Sol Ring
90%inclusion617 decks682 decks
4%synergy
Arcane Signet
65%inclusion444 decks682 decks
3%synergy
Glistening Sphere
46%inclusion311 decks682 decks
44%synergy
Mind Stone
33%inclusion226 decks682 decks
3%synergy
Charcoal Diamond
32%inclusion216 decks682 decks
9%synergy
Staff of Compleation
28%inclusion194 decks682 decks
27%synergy
Heraldic Banner
19%inclusion130 decks682 decks
14%synergy
The Soul Stone
17%inclusion22 decks129 decks
4%synergy
Caged Sun
16%inclusion110 decks682 decks
4%synergy
Thought Vessel
16%inclusion109 decks682 decks
-11%synergy
Fellwar Stone
15%inclusion103 decks682 decks
0%synergy
Lotus Petal
13%inclusion88 decks682 decks
5%synergy
Throne of Eldraine
11%inclusion77 decks682 decks
1%synergy
Commander's Sphere
10%inclusion70 decks682 decks
1%synergy
Mox Opal
10%inclusion70 decks682 decks
7%synergy
Everflowing Chalice
10%inclusion68 decks682 decks
4%synergy
Jeweled Lotus
8.4%inclusion57 decks682 decks
6%synergy
Thran Dynamo
7.6%inclusion52 decks682 decks
2%synergy
Mana Crypt
7.2%inclusion49 decks682 decks
5%synergy
Worn Powerstone
6.5%inclusion44 decks682 decks
2%synergy
Sceptre of Eternal Glory
6.2%inclusion42 decks682 decks
-3%synergy
Gilded Lotus
6.0%inclusion41 decks682 decks
0%synergy
Mox Diamond
5.6%inclusion38 decks682 decks
2%synergy
Nyx Lotus
5.1%inclusion35 decks682 decks
-2%synergy
Mox Jasper
5.0%inclusion10 decks200 decks
5%synergy
Lands
Swamp
95%inclusion649 decks682 decks
0%synergy
Myriad Landscape
23%inclusion160 decks682 decks
-3%synergy
Malakir Rebirth
18%inclusion122 decks682 decks
-5%synergy
Mirrex
16%inclusion107 decks682 decks
15%synergy
Cavern of Souls
16%inclusion107 decks682 decks
9%synergy
Fell the Profane
13%inclusion73 decks545 decks
-5%synergy
Opal Palace
7.9%inclusion54 decks682 decks
7%synergy
Urza's Cave
7.5%inclusion43 decks576 decks
-1%synergy
The Seedcore
7.0%inclusion48 decks682 decks
7%synergy
Snow-Covered Swamp
5.7%inclusion39 decks682 decks
-1%synergy
Polluted Delta
5.4%inclusion37 decks682 decks
2%synergy
Bloodstained Mire
5.4%inclusion37 decks682 decks
2%synergy
Verdant Catacombs
5.3%inclusion36 decks682 decks
2%synergy
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