Skithiryx, the Blight Dragon (Commander) - Upgraded Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #792
83decks
As CommanderAs CardAverage DeckDecks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Plague Stinger
76%inclusion63 decks83 decks
75%synergy
Plague Myr
76%inclusion63 decks83 decks
75%synergy
Infectious Inquiry
76%inclusion63 decks83 decks
73%synergy
Karn's Bastion
72%inclusion60 decks83 decks
68%synergy
Ichor Rats
67%inclusion56 decks83 decks
65%synergy
Vraska's Fall
67%inclusion56 decks83 decks
64%synergy
Whispering Specter
63%inclusion52 decks83 decks
62%synergy
Phyrexian Crusader
63%inclusion52 decks83 decks
62%synergy
Hand of the Praetors
59%inclusion49 decks83 decks
58%synergy
Drown in Ichor
60%inclusion50 decks83 decks
57%synergy
Top Cards
Dark Ritual
80%inclusion66 decks83 decks
13%synergy
Jet Medallion
78%inclusion65 decks83 decks
16%synergy
Crypt Ghast
69%inclusion57 decks83 decks
21%synergy
Swiftfoot Boots
64%inclusion53 decks83 decks
32%synergy
Sign in Blood
59%inclusion49 decks83 decks
24%synergy
Lashwrithe
57%inclusion47 decks83 decks
53%synergy
Phyresis Outbreak
57%inclusion47 decks83 decks
55%synergy
Phyrexian Arena
57%inclusion47 decks83 decks
17%synergy
Feed the Swarm
53%inclusion44 decks83 decks
3%synergy
Night's Whisper
51%inclusion42 decks83 decks
26%synergy
Game Changers
Demonic Tutor
45%inclusion37 decks83 decks
17%synergy
Vampiric Tutor
28%inclusion23 decks83 decks
7%synergy
Necropotence
17%inclusion14 decks83 decks
2%synergy
Ancient Tomb
13%inclusion11 decks83 decks
2%synergy
Bolas's Citadel
12%inclusion10 decks83 decks
-16%synergy
Mana Vault
12%inclusion10 decks83 decks
5%synergy
Imperial Seal
8.4%inclusion7 decks83 decks
1%synergy
The One Ring
8.4%inclusion7 decks83 decks
-1%synergy
Opposition Agent
6.0%inclusion5 decks83 decks
-3%synergy
Orcish Bowmasters
6.0%inclusion5 decks83 decks
-7%synergy
Creatures
Blightbelly Rat
49%inclusion41 decks83 decks
46%synergy
Reaper of Sheoldred
40%inclusion33 decks83 decks
39%synergy
Ichorclaw Myr
34%inclusion28 decks83 decks
33%synergy
Phyrexian Obliterator
33%inclusion27 decks83 decks
21%synergy
Flensermite
31%inclusion26 decks83 decks
31%synergy
K'rrik, Son of Yawgmoth
29%inclusion24 decks83 decks
10%synergy
Bilious Skulldweller
28%inclusion23 decks83 decks
27%synergy
Flesh-Eater Imp
28%inclusion23 decks83 decks
27%synergy
Yawgmoth, Thran Physician
27%inclusion22 decks83 decks
17%synergy
Core Prowler
24%inclusion20 decks83 decks
24%synergy
Corpse Cur
24%inclusion20 decks83 decks
24%synergy
Septic Rats
23%inclusion19 decks83 decks
21%synergy
Pestilent Syphoner
22%inclusion18 decks83 decks
21%synergy
Myr Convert
22%inclusion18 decks83 decks
21%synergy
Gulping Scraptrap
20%inclusion17 decks83 decks
20%synergy
Blightsteel Colossus
20%inclusion17 decks83 decks
20%synergy
Dread Presence
18%inclusion15 decks83 decks
4%synergy
Necropede
18%inclusion15 decks83 decks
18%synergy
Filth
17%inclusion14 decks83 decks
14%synergy
Dauthi Voidwalker
16%inclusion13 decks83 decks
0%synergy
Solemn Simulacrum
14%inclusion12 decks83 decks
-7%synergy
Dark Confidant
14%inclusion12 decks83 decks
7%synergy
Magus of the Coffers
14%inclusion12 decks83 decks
8%synergy
Gray Merchant of Asphodel
14%inclusion12 decks83 decks
-36%synergy
Necroskitter
14%inclusion12 decks83 decks
12%synergy
Nirkana Revenant
14%inclusion12 decks83 decks
4%synergy
Silent Arbiter
13%inclusion11 decks83 decks
12%synergy
Brass Squire
12%inclusion10 decks83 decks
12%synergy
Sheoldred's Headcleaver
12%inclusion10 decks83 decks
12%synergy
Massacre Girl, Known Killer
12%inclusion10 decks83 decks
8%synergy
Emeritus of Woe
12%inclusion3 decks26 decks
4%synergy
Grafted Butcher
11%inclusion9 decks83 decks
11%synergy
Sheoldred, Whispering One
11%inclusion9 decks83 decks
-1%synergy
Phyrexian Vatmother
11%inclusion9 decks83 decks
11%synergy
Leaden Myr
11%inclusion9 decks83 decks
5%synergy
Contagious Nim
10%inclusion8 decks83 decks
9%synergy
Maha, Its Feathers Night
10%inclusion8 decks83 decks
5%synergy
Boggart Trawler
10%inclusion8 decks83 decks
0%synergy
Burnished Hart
10%inclusion8 decks83 decks
3%synergy
Gwenom, Remorseless
8.8%inclusion6 decks68 decks
5%synergy
Phyrexian Juggernaut
8.4%inclusion7 decks83 decks
8%synergy
Blackcleave Goblin
7.2%inclusion6 decks83 decks
7%synergy
Vector Asp
7.2%inclusion6 decks83 decks
7%synergy
Toxic Nim
7.2%inclusion6 decks83 decks
7%synergy
Sheoldred, the Apocalypse
6.0%inclusion5 decks83 decks
-9%synergy
Defiler of Flesh
6.0%inclusion5 decks83 decks
2%synergy
Sheoldred
6.0%inclusion5 decks83 decks
0%synergy
Phyrexian Digester
6.0%inclusion5 decks83 decks
6%synergy
Virulent Silencer
5.7%inclusion4 decks70 decks
6%synergy
Surge Conductor
5.7%inclusion4 decks70 decks
6%synergy
Instants
Defile
43%inclusion36 decks83 decks
8%synergy
Withering Torment
39%inclusion32 decks83 decks
7%synergy
Whisper of the Dross
37%inclusion31 decks83 decks
35%synergy
Imp's Mischief
36%inclusion30 decks83 decks
11%synergy
Go for the Throat
35%inclusion29 decks83 decks
12%synergy
Deadly Rollick
34%inclusion28 decks83 decks
9%synergy
Tainted Strike
34%inclusion28 decks83 decks
31%synergy
Howl from Beyond
33%inclusion27 decks83 decks
32%synergy
Infernal Grasp
33%inclusion27 decks83 decks
7%synergy
Malakir Rebirth
29%inclusion24 decks83 decks
6%synergy
Archenemy's Charm
29%inclusion20 decks70 decks
20%synergy
Cabal Ritual
28%inclusion23 decks83 decks
9%synergy
Fell the Profane
25%inclusion21 decks83 decks
6%synergy
Dismember
25%inclusion21 decks83 decks
15%synergy
Grim Affliction
24%inclusion20 decks83 decks
22%synergy
Darkness
23%inclusion19 decks83 decks
13%synergy
Snuff Out
20%inclusion17 decks83 decks
7%synergy
Sudden Spoiling
19%inclusion16 decks83 decks
11%synergy
Astarion's Thirst
16%inclusion13 decks83 decks
14%synergy
Hatred
16%inclusion13 decks83 decks
15%synergy
Consuming Corruption
14%inclusion12 decks83 decks
-1%synergy
Anoint with Affliction
14%inclusion12 decks83 decks
14%synergy
Bitter Triumph
14%inclusion12 decks83 decks
5%synergy
Supernatural Stamina
13%inclusion11 decks83 decks
6%synergy
Baleful Mastery
13%inclusion11 decks83 decks
5%synergy
Force of Despair
12%inclusion10 decks83 decks
4%synergy
Hero's Downfall
11%inclusion9 decks83 decks
4%synergy
Sheoldred's Edict
11%inclusion9 decks83 decks
-4%synergy
Doom Blade
11%inclusion9 decks83 decks
4%synergy
Cut Down
10%inclusion8 decks83 decks
6%synergy
Withering Boon
10%inclusion8 decks83 decks
5%synergy
Undying Malice
10%inclusion8 decks83 decks
-0%synergy
Murder
10%inclusion8 decks83 decks
-0%synergy
Village Rites
8.4%inclusion7 decks83 decks
-17%synergy
Deadly Dispute
8.4%inclusion7 decks83 decks
-18%synergy
Culling the Weak
8.4%inclusion7 decks83 decks
-9%synergy
Soul Shatter
8.4%inclusion7 decks83 decks
-3%synergy
Armor of Shadows
8.4%inclusion7 decks83 decks
6%synergy
Unlikely Aid
8.4%inclusion7 decks83 decks
8%synergy
Hagra Mauling
7.2%inclusion6 decks83 decks
3%synergy
Fake Your Own Death
7.2%inclusion6 decks83 decks
-0%synergy
Stinging Study
6.0%inclusion5 decks83 decks
3%synergy
Undying Evil
6.0%inclusion5 decks83 decks
3%synergy
Tragic Slip
6.0%inclusion5 decks83 decks
-13%synergy
Sorceries
Toxic Deluge
43%inclusion36 decks83 decks
7%synergy
Crux of Fate
40%inclusion33 decks83 decks
38%synergy
Bubbling Muck
37%inclusion31 decks83 decks
22%synergy
Insatiable Avarice
31%inclusion26 decks83 decks
20%synergy
Read the Bones
29%inclusion24 decks83 decks
13%synergy
Vat Emergence
28%inclusion23 decks83 decks
26%synergy
Reanimate
28%inclusion23 decks83 decks
-12%synergy
Damnation
24%inclusion20 decks83 decks
4%synergy
Caress of Phyrexia
20%inclusion17 decks83 decks
20%synergy
Mutilate
19%inclusion16 decks83 decks
3%synergy
Grim Tutor
19%inclusion16 decks83 decks
8%synergy
Spread the Sickness
17%inclusion14 decks83 decks
16%synergy
Geth's Summons
17%inclusion14 decks83 decks
16%synergy
Diabolic Tutor
16%inclusion13 decks83 decks
2%synergy
Black Sun's Zenith
14%inclusion12 decks83 decks
9%synergy
Exsanguinate
13%inclusion11 decks83 decks
-11%synergy
Gix's Command
13%inclusion11 decks83 decks
11%synergy
Syphon Mind
13%inclusion11 decks83 decks
1%synergy
Blasphemous Edict
12%inclusion10 decks82 decks
-4%synergy
Praetor's Grasp
11%inclusion9 decks83 decks
7%synergy
Profane Tutor
10%inclusion8 decks83 decks
5%synergy
Feed the Infection
10%inclusion8 decks83 decks
9%synergy
Beseech the Mirror
10%inclusion8 decks83 decks
3%synergy
Beseech the Queen
8.4%inclusion7 decks83 decks
2%synergy
Decorum Dissertation
7.7%inclusion2 decks26 decks
2%synergy
Pox Plague
7.7%inclusion2 decks26 decks
2%synergy
Peer into the Abyss
7.2%inclusion6 decks83 decks
-3%synergy
Torment of Hailfire
7.2%inclusion6 decks83 decks
-8%synergy
Villainous Wrath
6.3%inclusion4 decks64 decks
4%synergy
Ambition's Cost
6.0%inclusion5 decks83 decks
3%synergy
In Garruk's Wake
6.0%inclusion5 decks83 decks
2%synergy
Utility Artifacts
Lightning Greaves
49%inclusion41 decks83 decks
16%synergy
Blackblade Reforged
48%inclusion40 decks83 decks
45%synergy
Nightmare Lash
45%inclusion37 decks83 decks
42%synergy
Contagion Clasp
42%inclusion35 decks83 decks
40%synergy
Sword of Truth and Justice
41%inclusion34 decks83 decks
40%synergy
Contagion Engine
36%inclusion30 decks83 decks
34%synergy
Commander's Plate
36%inclusion30 decks83 decks
30%synergy
Fireshrieker
33%inclusion27 decks83 decks
31%synergy
Champion's Helm
33%inclusion27 decks83 decks
30%synergy
Whispersilk Cloak
31%inclusion26 decks83 decks
25%synergy
Shadowspear
29%inclusion24 decks83 decks
25%synergy
Sword of the Animist
27%inclusion22 decks83 decks
23%synergy
The Darkness Crystal
24%inclusion18 decks74 decks
4%synergy
Hero's Blade
22%inclusion18 decks83 decks
21%synergy
Expedition Map
19%inclusion16 decks83 decks
8%synergy
Leyline Axe
18%inclusion15 decks82 decks
17%synergy
Cranial Plating
18%inclusion15 decks83 decks
15%synergy
Basilisk Collar
18%inclusion15 decks83 decks
15%synergy
Mithril Coat
16%inclusion13 decks83 decks
10%synergy
Pact Weapon
16%inclusion13 decks83 decks
14%synergy
Sword of Feast and Famine
16%inclusion13 decks83 decks
14%synergy
Brotherhood Regalia
16%inclusion13 decks83 decks
13%synergy
Genji Glove
15%inclusion11 decks72 decks
14%synergy
Wayfarer's Bauble
14%inclusion12 decks83 decks
-0%synergy
Trailblazer's Boots
13%inclusion11 decks83 decks
11%synergy
Hammer of Nazahn
13%inclusion11 decks83 decks
12%synergy
Inquisitor's Flail
12%inclusion10 decks83 decks
12%synergy
Throne of Geth
11%inclusion9 decks83 decks
11%synergy
Darksteel Plate
11%inclusion9 decks83 decks
9%synergy
Sword of Vengeance
11%inclusion9 decks83 decks
10%synergy
Grafted Exoskeleton
11%inclusion9 decks83 decks
10%synergy
Manifold Key
10%inclusion8 decks83 decks
8%synergy
Silver Shroud Costume
10%inclusion8 decks83 decks
8%synergy
Doc Ock's Tentacles
9.4%inclusion6 decks64 decks
9%synergy
Sword of Light and Shadow
8.4%inclusion7 decks83 decks
8%synergy
Sensei's Divining Top
8.4%inclusion7 decks83 decks
0%synergy
Strata Scythe
8.4%inclusion7 decks83 decks
8%synergy
Sword of Forge and Frontier
8.4%inclusion7 decks83 decks
8%synergy
Buster Sword
8.1%inclusion6 decks74 decks
7%synergy
Crawlspace
7.2%inclusion6 decks83 decks
6%synergy
Sword of Fire and Ice
7.2%inclusion6 decks83 decks
7%synergy
Vorpal Sword
7.2%inclusion6 decks83 decks
3%synergy
Prowler's Helm
7.2%inclusion6 decks83 decks
6%synergy
Helm of the Host
7.2%inclusion6 decks83 decks
6%synergy
Bontu's Monument
7.2%inclusion6 decks83 decks
-21%synergy
Pip-Boy 3000
6.0%inclusion5 decks83 decks
6%synergy
O-Naginata
6.0%inclusion5 decks83 decks
6%synergy
Sword of Hearth and Home
6.0%inclusion5 decks83 decks
5%synergy
Conqueror's Flail
6.0%inclusion5 decks83 decks
5%synergy
Grafted Wargear
6.0%inclusion5 decks83 decks
6%synergy
Enchantments
Necrogen Communion
45%inclusion37 decks83 decks
43%synergy
Black Market Connections
31%inclusion26 decks83 decks
7%synergy
Unspeakable Symbol
29%inclusion24 decks83 decks
28%synergy
Kaya's Ghostform
28%inclusion23 decks83 decks
18%synergy
No Mercy
19%inclusion16 decks83 decks
12%synergy
Phyresis
12%inclusion10 decks83 decks
10%synergy
Bad Moon
12%inclusion10 decks83 decks
9%synergy
Animate Dead
11%inclusion9 decks83 decks
-6%synergy
Super State
10%inclusion7 decks70 decks
10%synergy
Dauthi Embrace
10%inclusion8 decks83 decks
8%synergy
Black Market
7.2%inclusion6 decks83 decks
-14%synergy
Greed
6.0%inclusion5 decks83 decks
-1%synergy
Glistening Oil
6.0%inclusion5 decks83 decks
5%synergy
Phyrexian Reclamation
6.0%inclusion5 decks83 decks
-4%synergy
Endless Scream
6.0%inclusion5 decks83 decks
6%synergy
Planeswalkers
Vraska, Betrayal's Sting
45%inclusion37 decks83 decks
42%synergy
Liliana of the Dark Realms
33%inclusion27 decks83 decks
19%synergy
Utility Lands
Rogue's Passage
71%inclusion59 decks83 decks
52%synergy
Cabal Coffers
70%inclusion58 decks83 decks
15%synergy
Bojuka Bog
53%inclusion44 decks83 decks
6%synergy
Urborg, Tomb of Yawgmoth
52%inclusion43 decks83 decks
14%synergy
Shizo, Death's Storehouse
49%inclusion41 decks83 decks
39%synergy
Inkmoth Nexus
47%inclusion39 decks83 decks
46%synergy
Cabal Stronghold
35%inclusion29 decks83 decks
1%synergy
War Room
28%inclusion23 decks83 decks
12%synergy
Cathedral of War
24%inclusion20 decks83 decks
24%synergy
Castle Locthwain
23%inclusion19 decks83 decks
6%synergy
The Black Gate
19%inclusion16 decks83 decks
16%synergy
Urza's Saga
17%inclusion14 decks83 decks
9%synergy
Command Beacon
16%inclusion13 decks83 decks
7%synergy
Witch's Cottage
14%inclusion12 decks83 decks
-10%synergy
Minas Morgul, Dark Fortress
14%inclusion12 decks83 decks
12%synergy
Nykthos, Shrine to Nyx
14%inclusion12 decks83 decks
-15%synergy
Reliquary Tower
14%inclusion12 decks83 decks
-16%synergy
Spymaster's Vault
12%inclusion10 decks83 decks
2%synergy
Phyrexian Tower
11%inclusion9 decks83 decks
-15%synergy
Mortuary Mire
10%inclusion8 decks83 decks
-3%synergy
Temple of the False God
10%inclusion8 decks83 decks
2%synergy
Buried Ruin
8.4%inclusion7 decks83 decks
3%synergy
Vault of Whispers
7.2%inclusion6 decks83 decks
2%synergy
Takenuma, Abandoned Mire
7.2%inclusion6 decks83 decks
-8%synergy
Thespian's Stage
7.2%inclusion6 decks83 decks
2%synergy
Barren Moor
6.0%inclusion5 decks83 decks
-3%synergy
Maze of Ith
6.0%inclusion5 decks83 decks
3%synergy
Ebon Stronghold
6.0%inclusion5 decks83 decks
5%synergy
Deserted Temple
6.0%inclusion5 decks83 decks
2%synergy
Peat Bog
6.0%inclusion5 decks83 decks
4%synergy
Strip Mine
6.0%inclusion5 decks83 decks
3%synergy
Mana Artifacts
Sol Ring
92%inclusion76 decks83 decks
6%synergy
Arcane Signet
58%inclusion48 decks83 decks
-4%synergy
Glistening Sphere
42%inclusion35 decks83 decks
41%synergy
Mind Stone
37%inclusion31 decks83 decks
9%synergy
Staff of Compleation
34%inclusion28 decks83 decks
32%synergy
Charcoal Diamond
29%inclusion24 decks83 decks
7%synergy
The Soul Stone
20%inclusion14 decks69 decks
5%synergy
Heraldic Banner
19%inclusion16 decks83 decks
14%synergy
Thought Vessel
18%inclusion15 decks83 decks
-7%synergy
Everflowing Chalice
16%inclusion13 decks83 decks
10%synergy
Fellwar Stone
16%inclusion13 decks83 decks
2%synergy
Lotus Petal
13%inclusion11 decks83 decks
6%synergy
Throne of Eldraine
12%inclusion10 decks83 decks
3%synergy
Thran Dynamo
11%inclusion9 decks83 decks
5%synergy
Mox Opal
10%inclusion8 decks83 decks
6%synergy
Caged Sun
7.2%inclusion6 decks83 decks
-4%synergy
Worn Powerstone
7.2%inclusion6 decks83 decks
3%synergy
Sceptre of Eternal Glory
7.2%inclusion6 decks83 decks
-1%synergy
Hedron Archive
6.0%inclusion5 decks83 decks
3%synergy
Extraplanar Lens
6.0%inclusion5 decks83 decks
1%synergy
Lands
Swamp
94%inclusion78 decks83 decks
-1%synergy
Myriad Landscape
29%inclusion24 decks83 decks
4%synergy
Malakir Rebirth
29%inclusion24 decks83 decks
6%synergy
Fell the Profane
25%inclusion21 decks83 decks
6%synergy
Mirrex
16%inclusion13 decks83 decks
15%synergy
Urza's Cave
13%inclusion11 decks83 decks
5%synergy
Cavern of Souls
13%inclusion11 decks83 decks
6%synergy
Boggart Trawler
10%inclusion8 decks83 decks
0%synergy
Hagra Mauling
7.2%inclusion6 decks83 decks
3%synergy
Gemstone Caverns
7.2%inclusion6 decks83 decks
3%synergy
The Seedcore
6.0%inclusion5 decks83 decks
6%synergy
Opal Palace
6.0%inclusion5 decks83 decks
5%synergy
Snow-Covered Swamp
6.0%inclusion5 decks83 decks
-1%synergy
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