Skithiryx, the Blight Dragon (Commander) - Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #792
48decks
As CommanderAs CardAverage DeckDecks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Plague Stinger
81%inclusion39 decks48 decks
80%synergy
Plague Myr
75%inclusion36 decks48 decks
74%synergy
Hand of the Praetors
73%inclusion35 decks48 decks
72%synergy
Infectious Inquiry
71%inclusion34 decks48 decks
68%synergy
Ichor Rats
69%inclusion33 decks48 decks
66%synergy
Ichorclaw Myr
65%inclusion31 decks48 decks
64%synergy
Blightbelly Rat
67%inclusion32 decks48 decks
63%synergy
Drown in Ichor
67%inclusion32 decks48 decks
63%synergy
Whispering Specter
63%inclusion30 decks48 decks
62%synergy
Vraska's Fall
65%inclusion31 decks48 decks
61%synergy
Top Cards
Lashwrithe
63%inclusion30 decks48 decks
59%synergy
Core Prowler
60%inclusion29 decks48 decks
60%synergy
Feed the Swarm
60%inclusion29 decks48 decks
10%synergy
Bilious Skulldweller
60%inclusion29 decks48 decks
59%synergy
Phyrexian Crusader
60%inclusion29 decks48 decks
60%synergy
Dark Ritual
58%inclusion28 decks48 decks
-9%synergy
Corpse Cur
58%inclusion28 decks48 decks
58%synergy
Reaper of Sheoldred
56%inclusion27 decks48 decks
56%synergy
Swiftfoot Boots
56%inclusion27 decks48 decks
25%synergy
Phyrexian Arena
56%inclusion27 decks48 decks
17%synergy
Creatures
Flensermite
54%inclusion26 decks48 decks
54%synergy
Crypt Ghast
54%inclusion26 decks48 decks
7%synergy
Pestilent Syphoner
48%inclusion23 decks48 decks
47%synergy
Flesh-Eater Imp
44%inclusion21 decks48 decks
43%synergy
Myr Convert
42%inclusion20 decks48 decks
41%synergy
Septic Rats
42%inclusion20 decks48 decks
40%synergy
Phyrexian Obliterator
38%inclusion18 decks48 decks
26%synergy
Necropede
35%inclusion17 decks48 decks
35%synergy
Phyrexian Juggernaut
33%inclusion16 decks48 decks
33%synergy
K'rrik, Son of Yawgmoth
33%inclusion16 decks48 decks
14%synergy
Leaden Myr
33%inclusion16 decks48 decks
27%synergy
Solemn Simulacrum
27%inclusion13 decks48 decks
6%synergy
Contagious Nim
25%inclusion12 decks48 decks
25%synergy
Yawgmoth, Thran Physician
25%inclusion12 decks48 decks
15%synergy
Gulping Scraptrap
25%inclusion12 decks48 decks
24%synergy
Blightsteel Colossus
21%inclusion10 decks48 decks
20%synergy
Blackcleave Goblin
19%inclusion9 decks48 decks
19%synergy
Dread Presence
17%inclusion8 decks48 decks
3%synergy
Gray Merchant of Asphodel
17%inclusion8 decks48 decks
-34%synergy
Swamp Mosquito
17%inclusion8 decks48 decks
17%synergy
Sheoldred's Headcleaver
15%inclusion7 decks48 decks
14%synergy
Vector Asp
13%inclusion6 decks48 decks
12%synergy
Magus of the Coffers
13%inclusion6 decks48 decks
6%synergy
Necroskitter
13%inclusion6 decks48 decks
10%synergy
Brass Squire
13%inclusion6 decks48 decks
12%synergy
Nirkana Revenant
13%inclusion6 decks48 decks
2%synergy
Palladium Myr
13%inclusion6 decks48 decks
11%synergy
Burnished Hart
13%inclusion6 decks48 decks
5%synergy
Toxic Nim
13%inclusion6 decks48 decks
12%synergy
Silent Arbiter
10%inclusion5 decks48 decks
9%synergy
Defiler of Flesh
10%inclusion5 decks48 decks
7%synergy
Sheoldred, Whispering One
10%inclusion5 decks48 decks
-1%synergy
Nimraiser Paladin
10%inclusion5 decks48 decks
10%synergy
Massacre Girl, Known Killer
10%inclusion5 decks48 decks
7%synergy
Dark Confidant
8.3%inclusion4 decks48 decks
1%synergy
Grafted Butcher
8.3%inclusion4 decks48 decks
8%synergy
Scheming Aspirant
8.3%inclusion4 decks48 decks
8%synergy
Phyrexian Vatmother
8.3%inclusion4 decks48 decks
8%synergy
Gwenom, Remorseless
6.9%inclusion2 decks29 decks
3%synergy
Dune Mover
6.3%inclusion3 decks48 decks
6%synergy
Paragon of Open Graves
6.3%inclusion3 decks48 decks
6%synergy
Ornithopter of Paradise
6.3%inclusion3 decks48 decks
3%synergy
Phyrexian Digester
6.3%inclusion3 decks48 decks
6%synergy
Skinrender
6.3%inclusion3 decks48 decks
5%synergy
Suspicious Bookcase
6.3%inclusion3 decks48 decks
6%synergy
Zenos yae Galvus
6.3%inclusion2 decks32 decks
3%synergy
Hullcarver
6.3%inclusion2 decks32 decks
5%synergy
Surge Conductor
6.3%inclusion2 decks32 decks
6%synergy
Scavenger Regent
5.4%inclusion2 decks37 decks
5%synergy
Qarsi Revenant
5.4%inclusion2 decks37 decks
0%synergy
Instants
Howl from Beyond
50%inclusion24 decks48 decks
49%synergy
Defile
50%inclusion24 decks48 decks
14%synergy
Tainted Strike
48%inclusion23 decks48 decks
45%synergy
Whisper of the Dross
46%inclusion22 decks48 decks
43%synergy
Grim Affliction
46%inclusion22 decks48 decks
44%synergy
Go for the Throat
33%inclusion16 decks48 decks
11%synergy
Withering Torment
28%inclusion13 decks46 decks
-3%synergy
Imp's Mischief
27%inclusion13 decks48 decks
2%synergy
Dismember
25%inclusion12 decks48 decks
15%synergy
Doom Blade
23%inclusion11 decks48 decks
16%synergy
Virulent Wound
23%inclusion11 decks48 decks
22%synergy
Archenemy's Charm
22%inclusion7 decks32 decks
13%synergy
Snuff Out
21%inclusion10 decks48 decks
7%synergy
Infernal Grasp
21%inclusion10 decks48 decks
-4%synergy
Murder
19%inclusion9 decks48 decks
9%synergy
Malakir Rebirth
19%inclusion9 decks48 decks
-4%synergy
Anoint with Affliction
17%inclusion8 decks48 decks
16%synergy
Sugar Rush
17%inclusion8 decks48 decks
16%synergy
Hero's Downfall
15%inclusion7 decks48 decks
8%synergy
Unlikely Aid
15%inclusion7 decks48 decks
14%synergy
Astarion's Thirst
13%inclusion6 decks48 decks
11%synergy
Force of Despair
13%inclusion6 decks48 decks
5%synergy
Unnatural Endurance
13%inclusion6 decks48 decks
12%synergy
Supernatural Stamina
13%inclusion6 decks48 decks
5%synergy
Consuming Corruption
10%inclusion5 decks48 decks
-5%synergy
Cabal Ritual
10%inclusion5 decks48 decks
-8%synergy
Lash of Thorns
10%inclusion5 decks48 decks
10%synergy
Culling the Weak
10%inclusion5 decks48 decks
-7%synergy
Withering Boon
10%inclusion5 decks48 decks
6%synergy
Undying Malice
10%inclusion5 decks48 decks
0%synergy
Tragic Slip
10%inclusion5 decks48 decks
-9%synergy
Fell the Profane
8.3%inclusion4 decks48 decks
-11%synergy
Grotesque Mutation
8.3%inclusion4 decks48 decks
8%synergy
Hatred
8.3%inclusion4 decks48 decks
7%synergy
Grasp of Darkness
8.3%inclusion4 decks48 decks
7%synergy
Rush of Vitality
8.3%inclusion4 decks48 decks
8%synergy
Darkness
8.3%inclusion4 decks48 decks
-2%synergy
Professor's Warning
8.3%inclusion4 decks48 decks
7%synergy
Masterful Flourish
7.1%inclusion1 decks14 decks
6%synergy
Deadly Rollick
6.3%inclusion3 decks48 decks
-19%synergy
Geth's Verdict
6.3%inclusion3 decks48 decks
6%synergy
Sheoldred's Edict
6.3%inclusion3 decks48 decks
-9%synergy
Undying Evil
6.3%inclusion3 decks48 decks
3%synergy
Armor of Shadows
6.3%inclusion3 decks48 decks
4%synergy
Vampire's Bite
6.3%inclusion3 decks48 decks
6%synergy
Baleful Mastery
6.3%inclusion3 decks48 decks
-2%synergy
Maximum Overdrive
5.3%inclusion2 decks38 decks
4%synergy
Sorceries
Phyresis Outbreak
54%inclusion26 decks48 decks
53%synergy
Sign in Blood
48%inclusion23 decks48 decks
13%synergy
Night's Whisper
42%inclusion20 decks48 decks
17%synergy
Crux of Fate
40%inclusion19 decks48 decks
38%synergy
Caress of Phyrexia
40%inclusion19 decks48 decks
39%synergy
Vat Emergence
31%inclusion15 decks48 decks
30%synergy
Read the Bones
31%inclusion15 decks48 decks
15%synergy
Toxic Deluge
25%inclusion12 decks48 decks
-12%synergy
Mutilate
21%inclusion10 decks48 decks
5%synergy
Reanimate
21%inclusion10 decks48 decks
-19%synergy
Geth's Summons
21%inclusion10 decks48 decks
20%synergy
Spread the Sickness
19%inclusion9 decks48 decks
18%synergy
Diabolic Tutor
19%inclusion9 decks48 decks
5%synergy
Feed the Infection
17%inclusion8 decks48 decks
16%synergy
In Garruk's Wake
17%inclusion8 decks48 decks
13%synergy
Bubbling Muck
15%inclusion7 decks48 decks
-1%synergy
Exsanguinate
15%inclusion7 decks48 decks
-10%synergy
Pox Plague
14%inclusion2 decks14 decks
9%synergy
Black Sun's Zenith
13%inclusion6 decks48 decks
7%synergy
Ancient Craving
10%inclusion5 decks48 decks
8%synergy
Innocent Blood
8.3%inclusion4 decks48 decks
3%synergy
Ambition's Cost
8.3%inclusion4 decks48 decks
6%synergy
Syphon Mind
8.3%inclusion4 decks48 decks
-4%synergy
Blasphemous Edict
7.0%inclusion3 decks43 decks
-9%synergy
Praetor's Grasp
6.3%inclusion3 decks48 decks
2%synergy
Corrupt
6.3%inclusion3 decks48 decks
4%synergy
Nighthaze
6.3%inclusion3 decks48 decks
6%synergy
Damnation
6.3%inclusion3 decks48 decks
-14%synergy
Utility Artifacts
Blackblade Reforged
52%inclusion25 decks48 decks
49%synergy
Contagion Clasp
46%inclusion22 decks48 decks
44%synergy
Jet Medallion
44%inclusion21 decks48 decks
-19%synergy
Fireshrieker
42%inclusion20 decks48 decks
40%synergy
Nightmare Lash
40%inclusion19 decks48 decks
37%synergy
Whispersilk Cloak
38%inclusion18 decks48 decks
32%synergy
Champion's Helm
31%inclusion15 decks48 decks
29%synergy
Contagion Engine
29%inclusion14 decks48 decks
27%synergy
Trailblazer's Boots
29%inclusion14 decks48 decks
27%synergy
Lightning Greaves
27%inclusion13 decks48 decks
-7%synergy
Wayfarer's Bauble
25%inclusion12 decks48 decks
10%synergy
Hero's Blade
25%inclusion12 decks48 decks
25%synergy
The Darkness Crystal
22%inclusion7 decks32 decks
2%synergy
Leyline Axe
19%inclusion8 decks43 decks
18%synergy
Throne of Geth
17%inclusion8 decks48 decks
16%synergy
Strata Scythe
17%inclusion8 decks48 decks
16%synergy
Commander's Plate
17%inclusion8 decks48 decks
11%synergy
Sword of Vengeance
17%inclusion8 decks48 decks
16%synergy
Inquisitor's Flail
15%inclusion7 decks48 decks
14%synergy
Brotherhood Regalia
15%inclusion7 decks48 decks
12%synergy
Sword of the Animist
15%inclusion7 decks48 decks
11%synergy
Loxodon Warhammer
15%inclusion7 decks48 decks
13%synergy
Grafted Exoskeleton
15%inclusion7 decks48 decks
13%synergy
Nettlecyst
13%inclusion6 decks48 decks
12%synergy
Darksteel Plate
13%inclusion6 decks48 decks
11%synergy
Prowler's Helm
10%inclusion5 decks48 decks
10%synergy
Vorpal Sword
10%inclusion5 decks48 decks
7%synergy
Sword of Truth and Justice
10%inclusion5 decks48 decks
10%synergy
Expedition Map
10%inclusion5 decks48 decks
-1%synergy
Genji Glove
9.4%inclusion3 decks32 decks
8%synergy
Manifold Key
8.3%inclusion4 decks48 decks
7%synergy
Thran Power Suit
8.3%inclusion4 decks48 decks
8%synergy
O-Naginata
8.3%inclusion4 decks48 decks
8%synergy
Cranial Plating
8.3%inclusion4 decks48 decks
5%synergy
Shadowspear
8.3%inclusion4 decks48 decks
4%synergy
Bontu's Monument
8.3%inclusion4 decks48 decks
-20%synergy
Silver Shroud Costume
8.3%inclusion4 decks48 decks
7%synergy
Pact Weapon
8.3%inclusion4 decks48 decks
6%synergy
Adaptive Omnitool
7.7%inclusion3 decks39 decks
7%synergy
Bloodthorn Flail
6.3%inclusion3 decks48 decks
6%synergy
Pip-Boy 3000
6.3%inclusion3 decks48 decks
6%synergy
Whip of Erebos
6.3%inclusion3 decks48 decks
-5%synergy
Skullclamp
6.3%inclusion3 decks48 decks
-16%synergy
Mind Carver
6.3%inclusion3 decks48 decks
6%synergy
Prosthetic Injector
6.3%inclusion3 decks48 decks
6%synergy
Mask of Avacyn
6.3%inclusion3 decks48 decks
6%synergy
Bladed Battle-Fan
6.3%inclusion3 decks48 decks
6%synergy
Ring of Xathrid
6.3%inclusion3 decks48 decks
6%synergy
Batterskull
6.3%inclusion3 decks48 decks
6%synergy
Hammer of Nazahn
6.3%inclusion3 decks48 decks
5%synergy
Enchantments
Necrogen Communion
50%inclusion24 decks48 decks
48%synergy
Kaya's Ghostform
27%inclusion13 decks48 decks
17%synergy
Bad Moon
27%inclusion13 decks48 decks
24%synergy
Unspeakable Symbol
23%inclusion11 decks48 decks
22%synergy
Phyresis
19%inclusion9 decks48 decks
17%synergy
Relic Putrescence
17%inclusion8 decks48 decks
16%synergy
Fungal Fortitude
15%inclusion7 decks48 decks
13%synergy
Glistening Oil
13%inclusion6 decks48 decks
12%synergy
Dauthi Embrace
10%inclusion5 decks48 decks
9%synergy
Endless Scream
10%inclusion5 decks48 decks
10%synergy
Demonic Embrace
10%inclusion5 decks48 decks
10%synergy
Black Market Connections
10%inclusion5 decks48 decks
-14%synergy
Greed
8.3%inclusion4 decks48 decks
2%synergy
Black Market
8.3%inclusion4 decks48 decks
-12%synergy
Shade's Form
8.3%inclusion4 decks48 decks
8%synergy
No Mercy
8.3%inclusion4 decks48 decks
1%synergy
Demonic Vigor
6.3%inclusion3 decks48 decks
6%synergy
Phyrexian Scriptures
6.3%inclusion3 decks48 decks
5%synergy
Underworld Connections
6.3%inclusion3 decks48 decks
4%synergy
Necrosynthesis
6.3%inclusion3 decks48 decks
5%synergy
Eternal Thirst
6.3%inclusion3 decks48 decks
4%synergy
Snake Cult Initiation
6.3%inclusion3 decks48 decks
6%synergy
Oubliette
6.3%inclusion3 decks48 decks
3%synergy
Planeswalkers
Vraska, Betrayal's Sting
40%inclusion19 decks48 decks
37%synergy
Liliana of the Dark Realms
25%inclusion12 decks48 decks
11%synergy
Utility Lands
Rogue's Passage
56%inclusion27 decks48 decks
37%synergy
Karn's Bastion
52%inclusion25 decks48 decks
48%synergy
Bojuka Bog
44%inclusion21 decks48 decks
-3%synergy
Cabal Coffers
40%inclusion19 decks48 decks
-15%synergy
Inkmoth Nexus
38%inclusion18 decks48 decks
37%synergy
Cabal Stronghold
27%inclusion13 decks48 decks
-7%synergy
Shizo, Death's Storehouse
21%inclusion10 decks48 decks
11%synergy
Cathedral of War
21%inclusion10 decks48 decks
20%synergy
Witch's Cottage
21%inclusion10 decks48 decks
-4%synergy
Barren Moor
19%inclusion9 decks48 decks
9%synergy
Mortuary Mire
17%inclusion8 decks48 decks
4%synergy
Nykthos, Shrine to Nyx
17%inclusion8 decks48 decks
-13%synergy
War Room
15%inclusion7 decks48 decks
-1%synergy
Castle Locthwain
10%inclusion5 decks48 decks
-6%synergy
Urborg, Tomb of Yawgmoth
10%inclusion5 decks48 decks
-27%synergy
Vault of Whispers
8.3%inclusion4 decks48 decks
3%synergy
Phyrexian Tower
8.3%inclusion4 decks48 decks
-18%synergy
Command Beacon
8.3%inclusion4 decks48 decks
0%synergy
Reliquary Tower
8.3%inclusion4 decks48 decks
-22%synergy
Temple of the False God
8.3%inclusion4 decks48 decks
1%synergy
Ghost Quarter
6.3%inclusion3 decks48 decks
4%synergy
Buried Ruin
6.3%inclusion3 decks48 decks
1%synergy
The Dross Pits
6.3%inclusion3 decks48 decks
5%synergy
Spawning Pool
6.3%inclusion3 decks48 decks
6%synergy
Mana Artifacts
Sol Ring
85%inclusion41 decks48 decks
-0%synergy
Arcane Signet
67%inclusion32 decks48 decks
5%synergy
Charcoal Diamond
42%inclusion20 decks48 decks
20%synergy
Glistening Sphere
38%inclusion18 decks48 decks
36%synergy
Mind Stone
27%inclusion13 decks48 decks
-1%synergy
Staff of Compleation
25%inclusion12 decks48 decks
23%synergy
Caged Sun
19%inclusion9 decks48 decks
8%synergy
Heraldic Banner
17%inclusion8 decks48 decks
11%synergy
Worn Powerstone
13%inclusion6 decks48 decks
8%synergy
Everflowing Chalice
10%inclusion5 decks48 decks
5%synergy
Fellwar Stone
10%inclusion5 decks48 decks
-4%synergy
Commander's Sphere
8.3%inclusion4 decks48 decks
0%synergy
Hedron Archive
8.3%inclusion4 decks48 decks
5%synergy
Thought Vessel
8.3%inclusion4 decks48 decks
-17%synergy
Gilded Lotus
8.3%inclusion4 decks48 decks
3%synergy
Gauntlet of Power
6.3%inclusion3 decks48 decks
3%synergy
Throne of Eldraine
6.3%inclusion3 decks48 decks
-3%synergy
Thran Dynamo
6.3%inclusion3 decks48 decks
0%synergy
Star Compass
6.3%inclusion3 decks48 decks
5%synergy
Lands
Swamp
100%inclusion48 decks48 decks
5%synergy
Myriad Landscape
35%inclusion17 decks48 decks
10%synergy
Mirrex
19%inclusion9 decks48 decks
18%synergy
Malakir Rebirth
19%inclusion9 decks48 decks
-4%synergy
The Seedcore
10%inclusion5 decks48 decks
10%synergy
Fell the Profane
8.3%inclusion4 decks48 decks
-11%synergy
Urza's Cave
6.3%inclusion3 decks48 decks
-2%synergy
Opal Palace
6.3%inclusion3 decks48 decks
6%synergy
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