Skithiryx, the Blight Dragon (Commander) - Core

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Plague Stinger
68%inclusion208 decks305 decks
67%synergy
Infectious Inquiry
69%inclusion210 decks305 decks
66%synergy
Plague Myr
67%inclusion203 decks305 decks
65%synergy
Lashwrithe
69%inclusion211 decks305 decks
65%synergy
Ichor Rats
66%inclusion200 decks305 decks
62%synergy
Vraska's Fall
65%inclusion199 decks305 decks
62%synergy
Hand of the Praetors
61%inclusion185 decks305 decks
60%synergy
Whispering Specter
58%inclusion178 decks305 decks
58%synergy
Drown in Ichor
61%inclusion186 decks305 decks
57%synergy
Fireshrieker
56%inclusion172 decks305 decks
54%synergy
Top Cards
Dark Ritual
68%inclusion207 decks305 decks
1%synergy
Swiftfoot Boots
63%inclusion192 decks305 decks
31%synergy
Blackblade Reforged
56%inclusion172 decks305 decks
54%synergy
Blightbelly Rat
56%inclusion170 decks305 decks
52%synergy
Sign in Blood
55%inclusion168 decks305 decks
19%synergy
Howl from Beyond
54%inclusion166 decks305 decks
54%synergy
Nightmare Lash
53%inclusion163 decks305 decks
51%synergy
Reaper of Sheoldred
53%inclusion161 decks305 decks
52%synergy
Phyrexian Arena
52%inclusion159 decks305 decks
12%synergy
Feed the Swarm
51%inclusion157 decks305 decks
0%synergy
Game Changers
Necropotence
6.9%inclusion21 decks305 decks
-8%synergy
Creatures
Phyrexian Crusader
48%inclusion146 decks305 decks
47%synergy
Core Prowler
47%inclusion144 decks305 decks
47%synergy
Ichorclaw Myr
47%inclusion142 decks305 decks
46%synergy
Crypt Ghast
45%inclusion137 decks305 decks
-3%synergy
Flensermite
45%inclusion136 decks305 decks
44%synergy
Corpse Cur
43%inclusion131 decks305 decks
43%synergy
Bilious Skulldweller
42%inclusion127 decks305 decks
41%synergy
Flesh-Eater Imp
41%inclusion125 decks305 decks
40%synergy
Septic Rats
39%inclusion118 decks305 decks
37%synergy
Pestilent Syphoner
37%inclusion114 decks305 decks
37%synergy
Necropede
30%inclusion90 decks305 decks
29%synergy
Solemn Simulacrum
29%inclusion87 decks305 decks
5%synergy
Leaden Myr
29%inclusion87 decks305 decks
22%synergy
Phyrexian Obliterator
27%inclusion81 decks305 decks
15%synergy
Contagious Nim
26%inclusion78 decks305 decks
25%synergy
Myr Convert
25%inclusion77 decks305 decks
25%synergy
Blackcleave Goblin
22%inclusion67 decks305 decks
22%synergy
Gulping Scraptrap
21%inclusion65 decks305 decks
21%synergy
K'rrik, Son of Yawgmoth
21%inclusion65 decks305 decks
2%synergy
Gray Merchant of Asphodel
20%inclusion60 decks305 decks
-32%synergy
Phyrexian Juggernaut
19%inclusion58 decks305 decks
19%synergy
Dread Presence
16%inclusion48 decks305 decks
1%synergy
Toxic Nim
15%inclusion47 decks305 decks
15%synergy
Sheoldred's Headcleaver
15%inclusion45 decks305 decks
14%synergy
Defiler of Flesh
14%inclusion43 decks305 decks
10%synergy
Phyrexian Vatmother
14%inclusion42 decks305 decks
14%synergy
Magus of the Coffers
13%inclusion41 decks305 decks
6%synergy
Burnished Hart
13%inclusion41 decks305 decks
6%synergy
Blightsteel Colossus
13%inclusion39 decks305 decks
12%synergy
Brass Squire
12%inclusion38 decks305 decks
12%synergy
Paragon of Open Graves
11%inclusion34 decks305 decks
10%synergy
Silent Arbiter
11%inclusion33 decks305 decks
9%synergy
Necroskitter
11%inclusion33 decks305 decks
7%synergy
Grafted Butcher
10%inclusion31 decks305 decks
10%synergy
Yawgmoth, Thran Physician
10%inclusion30 decks305 decks
0%synergy
Nimraiser Paladin
10%inclusion30 decks305 decks
10%synergy
Vector Asp
10%inclusion29 decks305 decks
9%synergy
Swamp Mosquito
10%inclusion29 decks305 decks
9%synergy
Nirkana Revenant
10%inclusion29 decks305 decks
-2%synergy
Massacre Girl, Known Killer
10%inclusion29 decks305 decks
6%synergy
Sheoldred, Whispering One
9.2%inclusion28 decks305 decks
-3%synergy
Phyrexian Digester
9.2%inclusion28 decks305 decks
9%synergy
Murderous Rider
8.2%inclusion25 decks305 decks
2%synergy
Palladium Myr
8.2%inclusion25 decks305 decks
6%synergy
Scourge Servant
7.5%inclusion23 decks305 decks
7%synergy
Suspicious Bookcase
6.6%inclusion20 decks305 decks
6%synergy
Virulent Silencer
6.5%inclusion5 decks77 decks
6%synergy
Surge Conductor
6.5%inclusion5 decks77 decks
6%synergy
Scavenger Regent
6.3%inclusion7 decks112 decks
6%synergy
Feral Deathgorger
6.2%inclusion7 decks113 decks
6%synergy
Instants
Defile
51%inclusion155 decks305 decks
13%synergy
Whisper of the Dross
42%inclusion129 decks305 decks
39%synergy
Go for the Throat
41%inclusion125 decks305 decks
18%synergy
Grim Affliction
40%inclusion121 decks305 decks
37%synergy
Infernal Grasp
33%inclusion102 decks305 decks
8%synergy
Tainted Strike
33%inclusion102 decks305 decks
30%synergy
Sugar Rush
28%inclusion85 decks305 decks
27%synergy
Supernatural Stamina
26%inclusion80 decks305 decks
19%synergy
Dismember
24%inclusion72 decks305 decks
13%synergy
Doom Blade
22%inclusion68 decks305 decks
15%synergy
Withering Torment
20%inclusion44 decks217 decks
-11%synergy
Astarion's Thirst
19%inclusion59 decks305 decks
18%synergy
Virulent Wound
19%inclusion59 decks305 decks
19%synergy
Consuming Corruption
18%inclusion47 decks265 decks
2%synergy
Imp's Mischief
18%inclusion54 decks305 decks
-6%synergy
Sudden Spoiling
17%inclusion51 decks305 decks
7%synergy
Hero's Downfall
17%inclusion51 decks305 decks
10%synergy
Murder
16%inclusion49 decks305 decks
6%synergy
Unlikely Aid
16%inclusion49 decks305 decks
15%synergy
Anoint with Affliction
15%inclusion46 decks305 decks
14%synergy
Malakir Rebirth
15%inclusion45 decks305 decks
-8%synergy
Deadly Rollick
14%inclusion43 decks305 decks
-10%synergy
Tragic Slip
13%inclusion39 decks305 decks
-8%synergy
Undying Malice
11%inclusion35 decks305 decks
2%synergy
Cabal Ritual
11%inclusion33 decks305 decks
-7%synergy
Snuff Out
10%inclusion30 decks305 decks
-3%synergy
Professor's Warning
10%inclusion29 decks305 decks
8%synergy
Fell the Profane
9.4%inclusion25 decks266 decks
-9%synergy
Archenemy's Charm
9.1%inclusion7 decks77 decks
0%synergy
Rush of Vitality
8.9%inclusion27 decks305 decks
8%synergy
Soul Shatter
8.5%inclusion26 decks305 decks
-4%synergy
Sheoldred's Edict
8.2%inclusion25 decks305 decks
-6%synergy
Hatred
8.2%inclusion25 decks305 decks
7%synergy
Force of Despair
7.2%inclusion22 decks305 decks
-1%synergy
Darkness
7.2%inclusion22 decks305 decks
-2%synergy
Baleful Mastery
7.2%inclusion22 decks305 decks
-2%synergy
Undying Evil
6.6%inclusion20 decks305 decks
3%synergy
Not Dead After All
6.6%inclusion20 decks305 decks
-5%synergy
Deadly Dispute
6.2%inclusion19 decks305 decks
-18%synergy
Blood Pact
5.9%inclusion18 decks305 decks
2%synergy
Fatal Fissure
5.7%inclusion2 decks35 decks
6%synergy
Overkill
5.5%inclusion5 decks91 decks
-2%synergy
Grotesque Mutation
5.2%inclusion16 decks305 decks
5%synergy
Heartless Act
5.2%inclusion16 decks305 decks
3%synergy
Unnatural Endurance
5.2%inclusion16 decks305 decks
5%synergy
Sorceries
Phyresis Outbreak
46%inclusion140 decks305 decks
44%synergy
Night's Whisper
45%inclusion136 decks305 decks
20%synergy
Read the Bones
42%inclusion129 decks305 decks
25%synergy
Caress of Phyrexia
41%inclusion125 decks305 decks
40%synergy
Crux of Fate
39%inclusion119 decks305 decks
38%synergy
Vat Emergence
30%inclusion91 decks305 decks
28%synergy
Spread the Sickness
25%inclusion75 decks305 decks
24%synergy
Mutilate
24%inclusion72 decks305 decks
5%synergy
Toxic Deluge
23%inclusion69 decks305 decks
-15%synergy
Diabolic Tutor
21%inclusion63 decks305 decks
6%synergy
Bubbling Muck
20%inclusion61 decks305 decks
4%synergy
Feed the Infection
15%inclusion45 decks305 decks
14%synergy
Geth's Summons
15%inclusion45 decks305 decks
14%synergy
Black Sun's Zenith
13%inclusion39 decks305 decks
7%synergy
Reanimate
13%inclusion39 decks305 decks
-26%synergy
Exsanguinate
13%inclusion39 decks305 decks
-12%synergy
Insatiable Avarice
12%inclusion35 decks290 decks
0%synergy
Syphon Mind
11%inclusion35 decks305 decks
-1%synergy
Damnation
11%inclusion33 decks305 decks
-10%synergy
In Garruk's Wake
11%inclusion33 decks305 decks
7%synergy
Blasphemous Edict
9.3%inclusion18 decks194 decks
-8%synergy
Fell
7.5%inclusion19 decks252 decks
4%synergy
Ancient Craving
7.2%inclusion22 decks305 decks
5%synergy
Languish
7.2%inclusion22 decks305 decks
6%synergy
Duress
6.9%inclusion21 decks305 decks
0%synergy
Ambition's Cost
6.2%inclusion19 decks305 decks
3%synergy
Profane Tutor
6.2%inclusion19 decks305 decks
2%synergy
Necromantic Selection
5.2%inclusion16 decks305 decks
3%synergy
Utility Artifacts
Contagion Clasp
44%inclusion135 decks305 decks
42%synergy
Jet Medallion
41%inclusion124 decks305 decks
-20%synergy
Whispersilk Cloak
39%inclusion119 decks305 decks
33%synergy
Lightning Greaves
38%inclusion115 decks305 decks
4%synergy
Contagion Engine
32%inclusion99 decks305 decks
30%synergy
Hero's Blade
27%inclusion83 decks305 decks
27%synergy
Wayfarer's Bauble
23%inclusion70 decks305 decks
7%synergy
Trailblazer's Boots
22%inclusion68 decks305 decks
20%synergy
Champion's Helm
19%inclusion58 decks305 decks
17%synergy
The Darkness Crystal
18%inclusion17 decks94 decks
-2%synergy
Leyline Axe
18%inclusion34 decks194 decks
17%synergy
Sword of Truth and Justice
17%inclusion51 decks305 decks
16%synergy
Pact Weapon
17%inclusion51 decks305 decks
15%synergy
Grafted Exoskeleton
15%inclusion47 decks305 decks
14%synergy
Throne of Geth
15%inclusion46 decks305 decks
15%synergy
Strata Scythe
15%inclusion46 decks305 decks
14%synergy
Cranial Plating
15%inclusion46 decks305 decks
12%synergy
Sword of Vengeance
15%inclusion45 decks305 decks
14%synergy
Commander's Plate
14%inclusion44 decks305 decks
9%synergy
Prowler's Helm
13%inclusion41 decks305 decks
13%synergy
Genji Glove
13%inclusion12 decks91 decks
12%synergy
Doc Ock's Tentacles
13%inclusion8 decks62 decks
13%synergy
Brotherhood Regalia
13%inclusion32 decks255 decks
10%synergy
Sword of the Animist
12%inclusion38 decks305 decks
9%synergy
Bontu's Monument
12%inclusion37 decks305 decks
-16%synergy
Loxodon Warhammer
12%inclusion36 decks305 decks
10%synergy
Vorpal Sword
11%inclusion34 decks305 decks
7%synergy
Inquisitor's Flail
11%inclusion34 decks305 decks
11%synergy
Expedition Map
11%inclusion33 decks305 decks
-1%synergy
Shadowspear
10%inclusion30 decks305 decks
6%synergy
Mask of Avacyn
10%inclusion29 decks305 decks
9%synergy
O-Naginata
10%inclusion29 decks305 decks
9%synergy
Grafted Wargear
9.2%inclusion28 decks305 decks
9%synergy
Decimator Web
8.2%inclusion25 decks305 decks
8%synergy
Nettlecyst
7.2%inclusion22 decks305 decks
7%synergy
Mithril Coat
7.2%inclusion22 decks305 decks
2%synergy
Darksteel Plate
6.2%inclusion19 decks305 decks
4%synergy
Prosthetic Injector
5.9%inclusion18 decks305 decks
6%synergy
Lavaspur Boots
5.8%inclusion17 decks292 decks
4%synergy
Basilisk Collar
5.6%inclusion17 decks305 decks
3%synergy
Livewire Lash
5.6%inclusion17 decks305 decks
6%synergy
Buster Sword
5.4%inclusion5 decks92 decks
4%synergy
Hammer of Nazahn
5.2%inclusion16 decks305 decks
5%synergy
Enchantments
Necrogen Communion
44%inclusion133 decks305 decks
42%synergy
Kaya's Ghostform
32%inclusion98 decks305 decks
22%synergy
Unspeakable Symbol
27%inclusion81 decks305 decks
26%synergy
Bad Moon
24%inclusion74 decks305 decks
21%synergy
Relic Putrescence
20%inclusion62 decks305 decks
20%synergy
Fungal Fortitude
19%inclusion57 decks305 decks
17%synergy
Endless Scream
18%inclusion56 decks305 decks
18%synergy
Phyresis
16%inclusion50 decks305 decks
14%synergy
Shade's Form
13%inclusion41 decks305 decks
13%synergy
Black Market
12%inclusion36 decks305 decks
-9%synergy
Black Market Connections
11%inclusion33 decks305 decks
-13%synergy
Underworld Connections
10%inclusion32 decks305 decks
8%synergy
Dauthi Embrace
10%inclusion31 decks305 decks
8%synergy
No Mercy
10%inclusion30 decks305 decks
3%synergy
Greed
8.5%inclusion26 decks305 decks
1%synergy
Snake Cult Initiation
7.2%inclusion22 decks305 decks
7%synergy
Alien Symbiosis
6.8%inclusion4 decks59 decks
6%synergy
Glistening Oil
6.6%inclusion20 decks305 decks
6%synergy
Corpses of the Lost
5.6%inclusion17 decks305 decks
4%synergy
Planeswalkers
Vraska, Betrayal's Sting
31%inclusion95 decks305 decks
28%synergy
Liliana of the Dark Realms
19%inclusion59 decks305 decks
5%synergy
Utility Lands
Rogue's Passage
64%inclusion194 decks305 decks
45%synergy
Karn's Bastion
55%inclusion169 decks305 decks
51%synergy
Bojuka Bog
43%inclusion130 decks305 decks
-4%synergy
Cabal Coffers
37%inclusion114 decks305 decks
-18%synergy
Cabal Stronghold
27%inclusion81 decks305 decks
-9%synergy
Inkmoth Nexus
21%inclusion65 decks305 decks
20%synergy
Shizo, Death's Storehouse
21%inclusion65 decks305 decks
11%synergy
Urborg, Tomb of Yawgmoth
20%inclusion61 decks305 decks
-18%synergy
Cathedral of War
19%inclusion59 decks305 decks
19%synergy
War Room
13%inclusion40 decks305 decks
-3%synergy
Witch's Cottage
13%inclusion39 decks305 decks
-12%synergy
Castle Locthwain
12%inclusion37 decks305 decks
-5%synergy
Temple of the False God
10%inclusion32 decks305 decks
3%synergy
Mortuary Mire
9.2%inclusion28 decks305 decks
-4%synergy
The Black Gate
9.2%inclusion28 decks305 decks
6%synergy
Nykthos, Shrine to Nyx
9.2%inclusion28 decks305 decks
-21%synergy
Reliquary Tower
8.9%inclusion27 decks305 decks
-22%synergy
Barren Moor
8.5%inclusion26 decks305 decks
-2%synergy
Command Beacon
7.9%inclusion24 decks305 decks
0%synergy
Minas Morgul, Dark Fortress
7.2%inclusion22 decks305 decks
4%synergy
Secret Tunnel
5.3%inclusion2 decks38 decks
4%synergy
Mana Artifacts
Sol Ring
84%inclusion255 decks305 decks
-3%synergy
Arcane Signet
62%inclusion189 decks305 decks
0%synergy
Charcoal Diamond
41%inclusion124 decks305 decks
18%synergy
Mind Stone
37%inclusion114 decks305 decks
7%synergy
Glistening Sphere
32%inclusion99 decks305 decks
31%synergy
Heraldic Banner
22%inclusion66 decks305 decks
16%synergy
Caged Sun
18%inclusion54 decks305 decks
6%synergy
Fellwar Stone
16%inclusion48 decks305 decks
1%synergy
Thought Vessel
16%inclusion48 decks305 decks
-11%synergy
Staff of Compleation
15%inclusion47 decks305 decks
14%synergy
Commander's Sphere
15%inclusion45 decks305 decks
6%synergy
Gilded Lotus
13%inclusion40 decks305 decks
8%synergy
Everflowing Chalice
10%inclusion32 decks305 decks
5%synergy
Thran Dynamo
10%inclusion31 decks305 decks
4%synergy
Worn Powerstone
10%inclusion30 decks305 decks
6%synergy
Throne of Eldraine
7.5%inclusion23 decks305 decks
-3%synergy
Sceptre of Eternal Glory
6.6%inclusion20 decks305 decks
-2%synergy
Hedron Archive
5.2%inclusion16 decks305 decks
2%synergy
Lands
Swamp
98%inclusion298 decks305 decks
3%synergy
Myriad Landscape
28%inclusion84 decks305 decks
1%synergy
Malakir Rebirth
15%inclusion45 decks305 decks
-8%synergy
Mirrex
12%inclusion38 decks305 decks
12%synergy
Opal Palace
10%inclusion32 decks305 decks
10%synergy
Fell the Profane
9.4%inclusion25 decks266 decks
-9%synergy
Command Tower
5.9%inclusion18 decks305 decks
0%synergy
The Seedcore
5.2%inclusion16 decks305 decks
5%synergy
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