Skithiryx, the Blight Dragon (Commander) - Optimized

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
93decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Utility Lands
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Splinter's Technique
13%inclusion1 decks8 decks
12%synergy
Bitterbloom Bearer
2.1%inclusion1 decks47 decks
-2%synergy
High Synergy Cards
Plague Myr
62%inclusion58 decks93 decks
61%synergy
Plague Stinger
61%inclusion57 decks93 decks
60%synergy
Lashwrithe
60%inclusion56 decks93 decks
56%synergy
Infectious Inquiry
56%inclusion52 decks93 decks
53%synergy
Whispering Specter
53%inclusion49 decks93 decks
52%synergy
Commander's Plate
56%inclusion52 decks93 decks
50%synergy
Shizo, Death's Storehouse
60%inclusion56 decks93 decks
50%synergy
Phyrexian Crusader
49%inclusion46 decks93 decks
49%synergy
Inkmoth Nexus
49%inclusion46 decks93 decks
48%synergy
Hand of the Praetors
46%inclusion43 decks93 decks
45%synergy
Top Cards
Dark Ritual
90%inclusion84 decks93 decks
24%synergy
Jet Medallion
82%inclusion76 decks93 decks
21%synergy
Phyrexian Arena
62%inclusion58 decks93 decks
22%synergy
Crypt Ghast
61%inclusion57 decks93 decks
13%synergy
Deadly Rollick
60%inclusion56 decks93 decks
36%synergy
Toxic Deluge
56%inclusion52 decks93 decks
19%synergy
Feed the Swarm
54%inclusion50 decks93 decks
3%synergy
Cabal Ritual
54%inclusion50 decks93 decks
36%synergy
Black Market Connections
51%inclusion47 decks93 decks
27%synergy
Swiftfoot Boots
48%inclusion45 decks93 decks
17%synergy
Game Changers
Demonic Tutor
77%inclusion72 decks93 decks
50%synergy
Vampiric Tutor
69%inclusion64 decks93 decks
48%synergy
Ancient Tomb
55%inclusion51 decks93 decks
43%synergy
Necropotence
55%inclusion51 decks93 decks
40%synergy
Mana Vault
48%inclusion45 decks93 decks
42%synergy
Opposition Agent
46%inclusion43 decks93 decks
36%synergy
The One Ring
43%inclusion40 decks93 decks
33%synergy
Bolas's Citadel
40%inclusion37 decks93 decks
11%synergy
Chrome Mox
40%inclusion37 decks93 decks
34%synergy
Orcish Bowmasters
38%inclusion35 decks93 decks
24%synergy
Creatures
Ichor Rats
48%inclusion45 decks93 decks
45%synergy
Dauthi Voidwalker
44%inclusion41 decks93 decks
28%synergy
Sheoldred, the Apocalypse
32%inclusion30 decks93 decks
17%synergy
K'rrik, Son of Yawgmoth
30%inclusion28 decks93 decks
11%synergy
Phyrexian Obliterator
29%inclusion27 decks93 decks
18%synergy
Gray Merchant of Asphodel
28%inclusion26 decks93 decks
-24%synergy
Flesh-Eater Imp
26%inclusion24 decks93 decks
25%synergy
Yawgmoth, Thran Physician
24%inclusion22 decks93 decks
13%synergy
Blightbelly Rat
23%inclusion21 decks93 decks
19%synergy
Dark Confidant
23%inclusion21 decks93 decks
15%synergy
Flensermite
22%inclusion20 decks93 decks
21%synergy
Pestilent Syphoner
16%inclusion15 decks93 decks
15%synergy
Reaper of Sheoldred
16%inclusion15 decks93 decks
16%synergy
Myr Convert
16%inclusion15 decks93 decks
15%synergy
Ichorclaw Myr
16%inclusion15 decks93 decks
16%synergy
Solemn Simulacrum
15%inclusion14 decks93 decks
-8%synergy
Corpse Cur
14%inclusion13 decks93 decks
14%synergy
Septic Rats
14%inclusion13 decks93 decks
12%synergy
Nirkana Revenant
14%inclusion13 decks93 decks
3%synergy
Magus of the Coffers
13%inclusion12 decks93 decks
6%synergy
Core Prowler
13%inclusion12 decks93 decks
12%synergy
Blood Pet
13%inclusion12 decks93 decks
5%synergy
Bilious Skulldweller
12%inclusion11 decks93 decks
11%synergy
Sheoldred, Whispering One
12%inclusion11 decks93 decks
0%synergy
Blightsteel Colossus
12%inclusion11 decks93 decks
11%synergy
Gwenom, Remorseless
10%inclusion6 decks58 decks
7%synergy
Massacre Wurm
8.6%inclusion8 decks93 decks
-9%synergy
Phyrexian Vatmother
7.5%inclusion7 decks93 decks
7%synergy
Leaden Myr
7.5%inclusion7 decks93 decks
1%synergy
Maha, Its Feathers Night
6.5%inclusion6 decks93 decks
2%synergy
Dread Presence
6.5%inclusion6 decks93 decks
-8%synergy
Silent Arbiter
6.5%inclusion6 decks93 decks
5%synergy
Gulping Scraptrap
6.5%inclusion6 decks93 decks
6%synergy
Vito, Thorn of the Dusk Rose
6.5%inclusion6 decks93 decks
-4%synergy
Toxic Nim
6.5%inclusion6 decks93 decks
6%synergy
Contagious Nim
6.5%inclusion6 decks93 decks
6%synergy
Grafted Butcher
6.5%inclusion6 decks93 decks
6%synergy
Scheming Aspirant
6.5%inclusion6 decks93 decks
6%synergy
Agent Venom
5.7%inclusion3 decks53 decks
3%synergy
Necropede
5.4%inclusion5 decks93 decks
5%synergy
Ornithopter of Paradise
5.4%inclusion5 decks93 decks
3%synergy
Bloodgift Demon
5.4%inclusion5 decks93 decks
2%synergy
Instants
Imp's Mischief
46%inclusion43 decks93 decks
22%synergy
Vraska's Fall
46%inclusion43 decks93 decks
43%synergy
Dismember
42%inclusion39 decks93 decks
31%synergy
Howl from Beyond
38%inclusion35 decks93 decks
37%synergy
Infernal Grasp
38%inclusion35 decks93 decks
12%synergy
Withering Torment
37%inclusion34 decks92 decks
5%synergy
Malakir Rebirth
32%inclusion30 decks93 decks
10%synergy
Go for the Throat
31%inclusion29 decks93 decks
8%synergy
Snuff Out
29%inclusion27 decks93 decks
16%synergy
Tainted Strike
28%inclusion26 decks93 decks
25%synergy
Hatred
27%inclusion25 decks93 decks
26%synergy
Astarion's Thirst
23%inclusion21 decks93 decks
21%synergy
Sudden Spoiling
22%inclusion20 decks93 decks
12%synergy
Defile
22%inclusion20 decks93 decks
-16%synergy
Whisper of the Dross
20%inclusion19 decks93 decks
17%synergy
Baleful Mastery
20%inclusion19 decks93 decks
11%synergy
Cut Down
20%inclusion19 decks93 decks
16%synergy
Withering Boon
20%inclusion19 decks93 decks
16%synergy
Darkness
17%inclusion16 decks93 decks
8%synergy
Culling the Weak
16%inclusion15 decks93 decks
1%synergy
Grim Affliction
16%inclusion15 decks93 decks
14%synergy
Fell the Profane
15%inclusion14 decks93 decks
-4%synergy
Hero's Downfall
14%inclusion13 decks93 decks
7%synergy
Bitter Triumph
13%inclusion12 decks93 decks
3%synergy
Archenemy's Charm
13%inclusion8 decks63 decks
4%synergy
Force of Despair
12%inclusion11 decks93 decks
4%synergy
Sheoldred's Edict
11%inclusion10 decks93 decks
-4%synergy
Sugar Rush
8.6%inclusion8 decks93 decks
8%synergy
Supernatural Stamina
8.6%inclusion8 decks93 decks
1%synergy
Virulent Wound
8.6%inclusion8 decks93 decks
8%synergy
Tragic Slip
8.6%inclusion8 decks93 decks
-12%synergy
Murder
7.5%inclusion7 decks93 decks
-3%synergy
Doom Blade
6.5%inclusion6 decks93 decks
-1%synergy
Slaughter Pact
6.5%inclusion6 decks93 decks
4%synergy
Ad Nauseam
6.5%inclusion6 decks93 decks
4%synergy
Soul Shatter
6.5%inclusion6 decks93 decks
-6%synergy
Anoint with Affliction
5.4%inclusion5 decks93 decks
5%synergy
Unlikely Aid
5.4%inclusion5 decks93 decks
5%synergy
Sorceries
Phyresis Outbreak
45%inclusion42 decks93 decks
43%synergy
Damnation
45%inclusion42 decks93 decks
24%synergy
Bubbling Muck
44%inclusion41 decks93 decks
28%synergy
Crux of Fate
42%inclusion39 decks93 decks
41%synergy
Night's Whisper
41%inclusion38 decks93 decks
16%synergy
Drown in Ichor
41%inclusion38 decks93 decks
37%synergy
Grim Tutor
34%inclusion32 decks93 decks
23%synergy
Sign in Blood
33%inclusion31 decks93 decks
-3%synergy
Imperial Seal
33%inclusion31 decks93 decks
26%synergy
Reanimate
28%inclusion26 decks93 decks
-11%synergy
Caress of Phyrexia
20%inclusion19 decks93 decks
20%synergy
Mutilate
16%inclusion15 decks93 decks
-2%synergy
Diabolic Tutor
15%inclusion14 decks93 decks
0%synergy
Read the Bones
15%inclusion14 decks93 decks
-3%synergy
Insatiable Avarice
15%inclusion14 decks93 decks
3%synergy
Black Sun's Zenith
14%inclusion13 decks93 decks
8%synergy
Beseech the Mirror
14%inclusion13 decks93 decks
7%synergy
Profane Tutor
14%inclusion13 decks93 decks
10%synergy
Praetor's Grasp
13%inclusion12 decks93 decks
9%synergy
Torment of Hailfire
13%inclusion12 decks93 decks
-3%synergy
Beseech the Queen
13%inclusion12 decks93 decks
7%synergy
Blasphemous Edict
12%inclusion11 decks89 decks
-5%synergy
Gix's Command
12%inclusion11 decks93 decks
10%synergy
Exsanguinate
12%inclusion11 decks93 decks
-13%synergy
Vat Emergence
11%inclusion10 decks93 decks
9%synergy
Peer into the Abyss
8.6%inclusion8 decks93 decks
-2%synergy
Spread the Sickness
7.5%inclusion7 decks93 decks
7%synergy
Victimize
7.5%inclusion7 decks93 decks
-19%synergy
Duress
7.5%inclusion7 decks93 decks
1%synergy
Yawgmoth's Will
6.5%inclusion6 decks93 decks
3%synergy
Thoughtseize
6.5%inclusion6 decks93 decks
2%synergy
Syphon Mind
6.5%inclusion6 decks93 decks
-6%synergy
Decree of Pain
5.4%inclusion5 decks93 decks
0%synergy
Dark Petition
5.4%inclusion5 decks93 decks
1%synergy
Rise of the Dark Realms
5.4%inclusion5 decks93 decks
-7%synergy
Scheming Symmetry
5.4%inclusion5 decks93 decks
1%synergy
Utility Artifacts
Lightning Greaves
48%inclusion45 decks93 decks
15%synergy
Nightmare Lash
45%inclusion42 decks93 decks
43%synergy
Shadowspear
43%inclusion40 decks93 decks
39%synergy
Blackblade Reforged
40%inclusion37 decks93 decks
37%synergy
Sword of Truth and Justice
32%inclusion30 decks93 decks
31%synergy
Whispersilk Cloak
29%inclusion27 decks93 decks
23%synergy
Contagion Engine
27%inclusion25 decks93 decks
25%synergy
Champion's Helm
25%inclusion23 decks93 decks
23%synergy
The Darkness Crystal
24%inclusion17 decks70 decks
5%synergy
Fireshrieker
24%inclusion22 decks93 decks
22%synergy
Leyline Axe
22%inclusion20 decks89 decks
22%synergy
Sensei's Divining Top
22%inclusion20 decks93 decks
13%synergy
Pact Weapon
22%inclusion20 decks93 decks
19%synergy
Expedition Map
19%inclusion18 decks93 decks
7%synergy
Contagion Clasp
18%inclusion17 decks93 decks
16%synergy
Cranial Plating
18%inclusion17 decks93 decks
15%synergy
Doc Ock's Tentacles
17%inclusion9 decks52 decks
17%synergy
Sword of the Animist
17%inclusion16 decks93 decks
13%synergy
Mithril Coat
17%inclusion16 decks93 decks
12%synergy
Sword of Feast and Famine
17%inclusion16 decks93 decks
15%synergy
Wishclaw Talisman
16%inclusion15 decks93 decks
9%synergy
Hammer of Nazahn
16%inclusion15 decks93 decks
15%synergy
Sword of Wealth and Power
14%inclusion13 decks93 decks
13%synergy
Brotherhood Regalia
13%inclusion12 decks93 decks
10%synergy
Buster Sword
13%inclusion9 decks70 decks
12%synergy
Silver Shroud Costume
10%inclusion9 decks93 decks
9%synergy
Strata Scythe
10%inclusion9 decks93 decks
9%synergy
Thran Power Suit
10%inclusion9 decks93 decks
9%synergy
Genji Glove
8.8%inclusion6 decks68 decks
8%synergy
Aetherflux Reservoir
8.6%inclusion8 decks93 decks
-1%synergy
Bontu's Monument
8.6%inclusion8 decks93 decks
-19%synergy
Loxodon Warhammer
8.6%inclusion8 decks93 decks
7%synergy
Hero's Blade
8.6%inclusion8 decks93 decks
8%synergy
Grafted Exoskeleton
8.6%inclusion8 decks93 decks
7%synergy
Whip of Erebos
8.6%inclusion8 decks93 decks
-2%synergy
Trailblazer's Boots
8.6%inclusion8 decks93 decks
6%synergy
Wayfarer's Bauble
7.5%inclusion7 decks93 decks
-8%synergy
Manifold Key
7.5%inclusion7 decks93 decks
6%synergy
O-Naginata
7.5%inclusion7 decks93 decks
7%synergy
Vorpal Sword
6.5%inclusion6 decks93 decks
3%synergy
Strength-Testing Hammer
6.5%inclusion6 decks93 decks
6%synergy
Inquisitor's Flail
6.5%inclusion6 decks93 decks
6%synergy
Sword of Vengeance
6.5%inclusion6 decks93 decks
6%synergy
Winter Moon
5.4%inclusion5 decks93 decks
4%synergy
Sword of Fire and Ice
5.4%inclusion5 decks93 decks
5%synergy
Sword of Hearth and Home
5.4%inclusion5 decks93 decks
4%synergy
Conqueror's Flail
5.4%inclusion5 decks93 decks
5%synergy
Enchantments
Unspeakable Symbol
43%inclusion40 decks93 decks
42%synergy
Necrogen Communion
29%inclusion27 decks93 decks
27%synergy
Kaya's Ghostform
23%inclusion21 decks93 decks
12%synergy
Phyresis
18%inclusion17 decks93 decks
16%synergy
No Mercy
16%inclusion15 decks93 decks
9%synergy
Contamination
16%inclusion15 decks93 decks
13%synergy
The Meathook Massacre
13%inclusion12 decks93 decks
-4%synergy
Animate Dead
13%inclusion12 decks93 decks
-5%synergy
Super State
11%inclusion7 decks65 decks
11%synergy
Dauthi Embrace
10%inclusion9 decks93 decks
8%synergy
Oubliette
10%inclusion9 decks93 decks
7%synergy
Black Market
10%inclusion9 decks93 decks
-11%synergy
Haunted One
10%inclusion9 decks93 decks
7%synergy
Bitterblossom
10%inclusion9 decks93 decks
-3%synergy
Endless Scream
8.6%inclusion8 decks93 decks
8%synergy
Glistening Oil
8.6%inclusion8 decks93 decks
8%synergy
Snake Cult Initiation
8.6%inclusion8 decks93 decks
8%synergy
Alien Symbiosis
7.7%inclusion4 decks52 decks
7%synergy
Exquisite Blood
7.5%inclusion7 decks93 decks
-6%synergy
Infernal Darkness
7.5%inclusion7 decks93 decks
7%synergy
Phyrexian Reclamation
7.5%inclusion7 decks93 decks
-3%synergy
Bad Moon
7.5%inclusion7 decks93 decks
4%synergy
Relic Putrescence
6.5%inclusion6 decks93 decks
6%synergy
Leyline of the Void
6.5%inclusion6 decks93 decks
5%synergy
Shade's Form
5.4%inclusion5 decks93 decks
5%synergy
Fungal Fortitude
5.4%inclusion5 decks93 decks
4%synergy
Demonic Embrace
5.4%inclusion5 decks93 decks
5%synergy
Planeswalkers
Liliana of the Dark Realms
41%inclusion38 decks93 decks
27%synergy
Vraska, Betrayal's Sting
37%inclusion34 decks93 decks
34%synergy
Tezzeret, Cruel Captain
6.1%inclusion4 decks66 decks
5%synergy
Utility Lands
Cabal Coffers
82%inclusion76 decks93 decks
27%synergy
Urborg, Tomb of Yawgmoth
76%inclusion71 decks93 decks
39%synergy
Rogue's Passage
53%inclusion49 decks93 decks
34%synergy
Karn's Bastion
43%inclusion40 decks93 decks
39%synergy
Urza's Saga
37%inclusion34 decks93 decks
29%synergy
Bojuka Bog
35%inclusion33 decks93 decks
-11%synergy
Cabal Stronghold
35%inclusion33 decks93 decks
0%synergy
Nykthos, Shrine to Nyx
27%inclusion25 decks93 decks
-3%synergy
The Black Gate
25%inclusion23 decks93 decks
21%synergy
Command Beacon
16%inclusion15 decks93 decks
8%synergy
Castle Locthwain
16%inclusion15 decks93 decks
-1%synergy
Phyrexian Tower
15%inclusion14 decks93 decks
-9%synergy
Lake of the Dead
15%inclusion14 decks93 decks
10%synergy
Strip Mine
14%inclusion13 decks93 decks
11%synergy
Takenuma, Abandoned Mire
13%inclusion12 decks93 decks
-3%synergy
Cathedral of War
13%inclusion12 decks93 decks
13%synergy
Reliquary Tower
13%inclusion12 decks93 decks
-18%synergy
Homeward Path
12%inclusion11 decks93 decks
10%synergy
War Room
11%inclusion10 decks93 decks
-6%synergy
Minas Morgul, Dark Fortress
10%inclusion9 decks93 decks
7%synergy
Temple of the False God
8.6%inclusion8 decks93 decks
1%synergy
Deserted Temple
7.5%inclusion7 decks93 decks
3%synergy
Vault of Whispers
7.5%inclusion7 decks93 decks
2%synergy
Mortuary Mire
7.5%inclusion7 decks93 decks
-6%synergy
Witch's Cottage
7.5%inclusion7 decks93 decks
-17%synergy
Emergence Zone
6.5%inclusion6 decks93 decks
3%synergy
Inventors' Fair
6.5%inclusion6 decks93 decks
4%synergy
Wasteland
5.4%inclusion5 decks93 decks
4%synergy
Arcane Lighthouse
5.4%inclusion5 decks93 decks
3%synergy
Buried Ruin
5.4%inclusion5 decks93 decks
0%synergy
Crystal Vein
5.4%inclusion5 decks93 decks
3%synergy
Mana Artifacts
Sol Ring
98%inclusion91 decks93 decks
12%synergy
Arcane Signet
69%inclusion64 decks93 decks
7%synergy
The Soul Stone
41%inclusion24 decks58 decks
28%synergy
Mox Opal
41%inclusion38 decks93 decks
37%synergy
Lotus Petal
40%inclusion37 decks93 decks
32%synergy
Mox Diamond
29%inclusion27 decks93 decks
25%synergy
Glistening Sphere
28%inclusion26 decks93 decks
27%synergy
Mind Stone
26%inclusion24 decks93 decks
-4%synergy
Fellwar Stone
25%inclusion23 decks93 decks
10%synergy
Grim Monolith
23%inclusion21 decks93 decks
20%synergy
Staff of Compleation
22%inclusion20 decks93 decks
20%synergy
Throne of Eldraine
19%inclusion18 decks93 decks
9%synergy
Heraldic Banner
17%inclusion16 decks93 decks
12%synergy
Thought Vessel
17%inclusion16 decks93 decks
-9%synergy
Caged Sun
16%inclusion15 decks93 decks
4%synergy
Mox Amber
15%inclusion14 decks93 decks
11%synergy
Mox Jasper
12%inclusion10 decks84 decks
12%synergy
Extraplanar Lens
12%inclusion11 decks93 decks
7%synergy
Charcoal Diamond
11%inclusion10 decks93 decks
-12%synergy
Patchwork Banner
8.6%inclusion8 decks93 decks
4%synergy
Thran Dynamo
8.6%inclusion8 decks93 decks
3%synergy
Gilded Lotus
7.5%inclusion7 decks93 decks
2%synergy
Sceptre of Eternal Glory
7.5%inclusion7 decks93 decks
-1%synergy
Everflowing Chalice
6.5%inclusion6 decks93 decks
1%synergy
Gauntlet of Power
5.4%inclusion5 decks93 decks
2%synergy
Mox Tantalite
5.4%inclusion5 decks93 decks
5%synergy
Lands
Swamp
95%inclusion88 decks93 decks
0%synergy
Cavern of Souls
35%inclusion33 decks93 decks
29%synergy
Malakir Rebirth
32%inclusion30 decks93 decks
10%synergy
Gemstone Caverns
26%inclusion24 decks93 decks
21%synergy
Myriad Landscape
15%inclusion14 decks93 decks
-11%synergy
Fell the Profane
15%inclusion14 decks93 decks
-4%synergy
Mirrex
14%inclusion13 decks93 decks
13%synergy
Marsh Flats
14%inclusion13 decks93 decks
11%synergy
Polluted Delta
14%inclusion13 decks93 decks
11%synergy
Bloodstained Mire
14%inclusion13 decks93 decks
10%synergy
Verdant Catacombs
13%inclusion12 decks93 decks
10%synergy
Urza's Cave
8.6%inclusion8 decks93 decks
0%synergy
Command Tower
7.5%inclusion7 decks93 decks
2%synergy
Snow-Covered Swamp
7.5%inclusion7 decks93 decks
1%synergy
Talon Gates of Madara
5.4%inclusion5 decks93 decks
4%synergy
Prismatic Vista
5.4%inclusion5 decks93 decks
3%synergy
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