Skithiryx, the Blight Dragon (Commander) - Optimized

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #792
110decks
As CommanderAs CardAverage DeckDecks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Plague Myr
65%inclusion71 decks110 decks
63%synergy
Plague Stinger
60%inclusion66 decks110 decks
59%synergy
Infectious Inquiry
57%inclusion63 decks110 decks
55%synergy
Lashwrithe
55%inclusion61 decks110 decks
52%synergy
Whispering Specter
51%inclusion56 decks110 decks
50%synergy
Shizo, Death's Storehouse
60%inclusion66 decks110 decks
50%synergy
Phyrexian Crusader
49%inclusion54 decks110 decks
48%synergy
Ichor Rats
50%inclusion55 decks110 decks
47%synergy
Inkmoth Nexus
47%inclusion52 decks110 decks
46%synergy
Vraska's Fall
49%inclusion54 decks110 decks
46%synergy
Top Cards
Dark Ritual
90%inclusion99 decks110 decks
23%synergy
Jet Medallion
80%inclusion88 decks110 decks
18%synergy
Deadly Rollick
62%inclusion68 decks110 decks
37%synergy
Phyrexian Arena
62%inclusion68 decks110 decks
22%synergy
Crypt Ghast
60%inclusion66 decks110 decks
13%synergy
Toxic Deluge
56%inclusion62 decks110 decks
20%synergy
Swiftfoot Boots
54%inclusion59 decks110 decks
22%synergy
Commander's Plate
52%inclusion57 decks110 decks
46%synergy
Lightning Greaves
51%inclusion56 decks110 decks
17%synergy
Cabal Ritual
49%inclusion54 decks110 decks
31%synergy
Game Changers
Demonic Tutor
75%inclusion83 decks110 decks
48%synergy
Vampiric Tutor
68%inclusion75 decks110 decks
47%synergy
Ancient Tomb
52%inclusion57 decks110 decks
40%synergy
Necropotence
50%inclusion55 decks110 decks
35%synergy
Opposition Agent
45%inclusion50 decks110 decks
36%synergy
Mana Vault
44%inclusion48 decks110 decks
37%synergy
Bolas's Citadel
39%inclusion43 decks110 decks
11%synergy
The One Ring
38%inclusion42 decks110 decks
29%synergy
Chrome Mox
35%inclusion39 decks110 decks
29%synergy
Orcish Bowmasters
35%inclusion38 decks110 decks
21%synergy
Creatures
Hand of the Praetors
46%inclusion51 decks110 decks
46%synergy
Dauthi Voidwalker
43%inclusion47 decks110 decks
27%synergy
Phyrexian Obliterator
32%inclusion35 decks110 decks
21%synergy
Sheoldred, the Apocalypse
30%inclusion33 decks110 decks
15%synergy
K'rrik, Son of Yawgmoth
29%inclusion32 decks110 decks
10%synergy
Gray Merchant of Asphodel
26%inclusion29 decks110 decks
-24%synergy
Flesh-Eater Imp
25%inclusion28 decks110 decks
25%synergy
Blightbelly Rat
25%inclusion27 decks110 decks
21%synergy
Flensermite
24%inclusion26 decks110 decks
23%synergy
Yawgmoth, Thran Physician
24%inclusion26 decks110 decks
14%synergy
Dark Confidant
23%inclusion25 decks110 decks
15%synergy
Ichorclaw Myr
20%inclusion22 decks110 decks
20%synergy
Myr Convert
18%inclusion20 decks110 decks
17%synergy
Pestilent Syphoner
17%inclusion19 decks110 decks
17%synergy
Reaper of Sheoldred
16%inclusion18 decks110 decks
16%synergy
Nirkana Revenant
15%inclusion17 decks110 decks
5%synergy
Blood Pet
15%inclusion17 decks110 decks
7%synergy
Core Prowler
15%inclusion16 decks110 decks
14%synergy
Bilious Skulldweller
15%inclusion16 decks110 decks
14%synergy
Corpse Cur
15%inclusion16 decks110 decks
14%synergy
Septic Rats
15%inclusion16 decks110 decks
13%synergy
Solemn Simulacrum
14%inclusion15 decks110 decks
-8%synergy
Blightsteel Colossus
14%inclusion15 decks110 decks
13%synergy
Emeritus of Woe
11%inclusion3 decks27 decks
3%synergy
Magus of the Coffers
11%inclusion12 decks110 decks
4%synergy
Sheoldred, Whispering One
11%inclusion12 decks110 decks
-1%synergy
Gwenom, Remorseless
10%inclusion8 decks77 decks
7%synergy
Leaden Myr
8.2%inclusion9 decks110 decks
2%synergy
Necropede
8.2%inclusion9 decks110 decks
8%synergy
Contagious Nim
7.3%inclusion8 decks110 decks
7%synergy
Silent Arbiter
7.3%inclusion8 decks110 decks
6%synergy
Massacre Wurm
7.3%inclusion8 decks110 decks
-10%synergy
Gulping Scraptrap
7.3%inclusion8 decks110 decks
7%synergy
Phyrexian Juggernaut
6.4%inclusion7 decks110 decks
6%synergy
Ornithopter of Paradise
6.4%inclusion7 decks110 decks
4%synergy
Necroskitter
6.4%inclusion7 decks110 decks
3%synergy
Toxic Nim
6.4%inclusion7 decks110 decks
6%synergy
Phyrexian Vatmother
6.4%inclusion7 decks110 decks
6%synergy
Agent Venom
5.5%inclusion4 decks73 decks
3%synergy
Dread Presence
5.5%inclusion6 decks110 decks
-8%synergy
Erebos, God of the Dead
5.5%inclusion6 decks110 decks
1%synergy
Grafted Butcher
5.5%inclusion6 decks110 decks
5%synergy
Vito, Thorn of the Dusk Rose
5.5%inclusion6 decks110 decks
-5%synergy
Mikaeus, the Unhallowed
5.5%inclusion6 decks110 decks
-2%synergy
Nimraiser Paladin
5.5%inclusion6 decks110 decks
5%synergy
Scheming Aspirant
5.5%inclusion6 decks110 decks
5%synergy
Madame Null, Power Broker
5.3%inclusion2 decks38 decks
4%synergy
Surge Conductor
5.0%inclusion4 decks80 decks
5%synergy
Instants
Imp's Mischief
46%inclusion51 decks110 decks
21%synergy
Dismember
45%inclusion49 decks110 decks
34%synergy
Infernal Grasp
40%inclusion44 decks110 decks
15%synergy
Howl from Beyond
36%inclusion40 decks110 decks
36%synergy
Withering Torment
35%inclusion38 decks109 decks
3%synergy
Go for the Throat
34%inclusion37 decks110 decks
11%synergy
Snuff Out
30%inclusion33 decks110 decks
17%synergy
Malakir Rebirth
29%inclusion32 decks110 decks
6%synergy
Tainted Strike
27%inclusion30 decks110 decks
24%synergy
Hatred
25%inclusion28 decks110 decks
24%synergy
Astarion's Thirst
22%inclusion24 decks110 decks
20%synergy
Whisper of the Dross
22%inclusion24 decks110 decks
19%synergy
Defile
22%inclusion24 decks110 decks
-14%synergy
Withering Boon
22%inclusion24 decks110 decks
17%synergy
Baleful Mastery
21%inclusion23 decks110 decks
13%synergy
Sudden Spoiling
20%inclusion22 decks110 decks
11%synergy
Cut Down
19%inclusion21 decks110 decks
15%synergy
Grim Affliction
18%inclusion20 decks110 decks
16%synergy
Darkness
18%inclusion20 decks110 decks
8%synergy
Culling the Weak
17%inclusion19 decks110 decks
0%synergy
Bitter Triumph
15%inclusion17 decks110 decks
6%synergy
Hero's Downfall
15%inclusion16 decks110 decks
8%synergy
Fell the Profane
15%inclusion16 decks110 decks
-5%synergy
Sheoldred's Edict
14%inclusion15 decks110 decks
-1%synergy
Archenemy's Charm
13%inclusion11 decks82 decks
5%synergy
Force of Despair
11%inclusion12 decks110 decks
3%synergy
Supernatural Stamina
10%inclusion11 decks110 decks
2%synergy
Virulent Wound
9.1%inclusion10 decks110 decks
9%synergy
Slaughter Pact
8.2%inclusion9 decks110 decks
6%synergy
Sugar Rush
7.3%inclusion8 decks110 decks
7%synergy
Tragic Slip
6.4%inclusion7 decks110 decks
-13%synergy
Ad Nauseam
6.4%inclusion7 decks110 decks
4%synergy
Entomb
5.5%inclusion6 decks110 decks
-7%synergy
Unlikely Aid
5.5%inclusion6 decks110 decks
5%synergy
Fake Your Own Death
5.5%inclusion6 decks110 decks
-2%synergy
Sorceries
Feed the Swarm
47%inclusion52 decks110 decks
-3%synergy
Bubbling Muck
45%inclusion50 decks110 decks
30%synergy
Phyresis Outbreak
44%inclusion48 decks110 decks
42%synergy
Damnation
42%inclusion46 decks110 decks
22%synergy
Drown in Ichor
41%inclusion45 decks110 decks
37%synergy
Crux of Fate
40%inclusion44 decks110 decks
39%synergy
Night's Whisper
37%inclusion41 decks110 decks
12%synergy
Sign in Blood
34%inclusion37 decks110 decks
-1%synergy
Grim Tutor
34%inclusion37 decks110 decks
22%synergy
Reanimate
31%inclusion34 decks110 decks
-9%synergy
Imperial Seal
30%inclusion33 decks110 decks
23%synergy
Caress of Phyrexia
23%inclusion25 decks110 decks
22%synergy
Diabolic Tutor
17%inclusion19 decks110 decks
3%synergy
Read the Bones
15%inclusion17 decks110 decks
-1%synergy
Mutilate
15%inclusion16 decks110 decks
-2%synergy
Black Sun's Zenith
14%inclusion15 decks110 decks
8%synergy
Torment of Hailfire
14%inclusion15 decks110 decks
-2%synergy
Beseech the Queen
14%inclusion15 decks110 decks
8%synergy
Blasphemous Edict
13%inclusion14 decks106 decks
-3%synergy
Praetor's Grasp
13%inclusion14 decks110 decks
9%synergy
Exsanguinate
13%inclusion14 decks110 decks
-12%synergy
Insatiable Avarice
13%inclusion14 decks110 decks
1%synergy
Profane Tutor
12%inclusion13 decks110 decks
8%synergy
Beseech the Mirror
12%inclusion13 decks110 decks
5%synergy
Pox Plague
11%inclusion3 decks27 decks
6%synergy
Vat Emergence
10%inclusion11 decks110 decks
9%synergy
Yawgmoth's Will
9.1%inclusion10 decks110 decks
6%synergy
Gix's Command
9.1%inclusion10 decks110 decks
7%synergy
Peer into the Abyss
8.2%inclusion9 decks110 decks
-2%synergy
Thoughtseize
8.2%inclusion9 decks110 decks
4%synergy
Diabolic Intent
6.4%inclusion7 decks110 decks
-9%synergy
Duress
6.4%inclusion7 decks110 decks
-0%synergy
Rise of the Dark Realms
6.4%inclusion7 decks110 decks
-7%synergy
Spread the Sickness
5.5%inclusion6 decks110 decks
5%synergy
Decree of Pain
5.5%inclusion6 decks110 decks
0%synergy
In Garruk's Wake
5.5%inclusion6 decks110 decks
2%synergy
Syphon Mind
5.5%inclusion6 decks110 decks
-7%synergy
Dark Petition
5.5%inclusion6 decks110 decks
2%synergy
Splinter's Technique
5.3%inclusion2 decks38 decks
3%synergy
Utility Artifacts
Nightmare Lash
43%inclusion47 decks110 decks
40%synergy
Shadowspear
43%inclusion47 decks110 decks
39%synergy
Blackblade Reforged
43%inclusion47 decks110 decks
40%synergy
Sword of Truth and Justice
32%inclusion35 decks110 decks
31%synergy
Whispersilk Cloak
28%inclusion31 decks110 decks
22%synergy
Contagion Engine
26%inclusion29 decks110 decks
25%synergy
The Darkness Crystal
24%inclusion21 decks88 decks
4%synergy
Champion's Helm
24%inclusion26 decks110 decks
21%synergy
Contagion Clasp
23%inclusion25 decks110 decks
21%synergy
Fireshrieker
23%inclusion25 decks110 decks
21%synergy
Sensei's Divining Top
22%inclusion24 decks110 decks
14%synergy
Leyline Axe
22%inclusion23 decks106 decks
21%synergy
Pact Weapon
21%inclusion23 decks110 decks
19%synergy
Cranial Plating
19%inclusion21 decks110 decks
16%synergy
Expedition Map
19%inclusion21 decks110 decks
8%synergy
Mithril Coat
18%inclusion20 decks110 decks
13%synergy
Doc Ock's Tentacles
17%inclusion12 decks72 decks
16%synergy
Sword of Feast and Famine
16%inclusion18 decks110 decks
15%synergy
Hammer of Nazahn
15%inclusion17 decks110 decks
15%synergy
Sword of Wealth and Power
14%inclusion15 decks110 decks
13%synergy
Sword of the Animist
14%inclusion15 decks110 decks
10%synergy
Buster Sword
13%inclusion11 decks88 decks
12%synergy
Wishclaw Talisman
11%inclusion12 decks110 decks
4%synergy
Brotherhood Regalia
11%inclusion12 decks110 decks
8%synergy
Hero's Blade
11%inclusion12 decks110 decks
10%synergy
Whip of Erebos
10%inclusion11 decks110 decks
-1%synergy
Bontu's Monument
10%inclusion11 decks110 decks
-18%synergy
Loxodon Warhammer
10%inclusion11 decks110 decks
9%synergy
Silver Shroud Costume
10%inclusion11 decks110 decks
9%synergy
Aetherflux Reservoir
9.1%inclusion10 decks110 decks
-0%synergy
Strata Scythe
9.1%inclusion10 decks110 decks
8%synergy
O-Naginata
9.1%inclusion10 decks110 decks
9%synergy
Grafted Exoskeleton
9.1%inclusion10 decks110 decks
8%synergy
Inquisitor's Flail
9.1%inclusion10 decks110 decks
9%synergy
Trailblazer's Boots
8.2%inclusion9 decks110 decks
6%synergy
Thran Power Suit
8.2%inclusion9 decks110 decks
8%synergy
Genji Glove
8.1%inclusion7 decks86 decks
7%synergy
Winter Moon
7.3%inclusion8 decks110 decks
6%synergy
Strength-Testing Hammer
6.4%inclusion7 decks110 decks
6%synergy
Torpor Orb
6.4%inclusion7 decks110 decks
5%synergy
Throne of Geth
6.4%inclusion7 decks110 decks
6%synergy
Skullclamp
6.4%inclusion7 decks110 decks
-16%synergy
Wayfarer's Bauble
5.5%inclusion6 decks110 decks
-9%synergy
Manifold Key
5.5%inclusion6 decks110 decks
4%synergy
Sword of Hearth and Home
5.5%inclusion6 decks110 decks
4%synergy
Conqueror's Flail
5.5%inclusion6 decks110 decks
5%synergy
Vorpal Sword
5.5%inclusion6 decks110 decks
2%synergy
Basilisk Collar
5.5%inclusion6 decks110 decks
3%synergy
Sword of Vengeance
5.5%inclusion6 decks110 decks
5%synergy
Enchantments
Black Market Connections
46%inclusion51 decks110 decks
22%synergy
Unspeakable Symbol
44%inclusion48 decks110 decks
43%synergy
Necrogen Communion
25%inclusion28 decks110 decks
24%synergy
Phyresis
20%inclusion22 decks110 decks
18%synergy
Kaya's Ghostform
20%inclusion22 decks110 decks
10%synergy
Contamination
17%inclusion19 decks110 decks
14%synergy
No Mercy
15%inclusion17 decks110 decks
8%synergy
Super State
13%inclusion11 decks84 decks
13%synergy
Animate Dead
12%inclusion13 decks110 decks
-5%synergy
Bitterblossom
12%inclusion13 decks110 decks
-1%synergy
Endless Scream
11%inclusion12 decks110 decks
11%synergy
Dauthi Embrace
10%inclusion11 decks110 decks
8%synergy
The Meathook Massacre
9.1%inclusion10 decks110 decks
-8%synergy
Black Market
9.1%inclusion10 decks110 decks
-12%synergy
Snake Cult Initiation
9.1%inclusion10 decks110 decks
9%synergy
Phyrexian Reclamation
8.2%inclusion9 decks110 decks
-2%synergy
Haunted One
8.2%inclusion9 decks110 decks
6%synergy
Glistening Oil
8.2%inclusion9 decks110 decks
7%synergy
Oubliette
8.2%inclusion9 decks110 decks
5%synergy
Exquisite Blood
8.2%inclusion9 decks110 decks
-5%synergy
Leyline of the Void
7.3%inclusion8 decks110 decks
6%synergy
Shade's Form
6.4%inclusion7 decks110 decks
6%synergy
Infernal Darkness
6.4%inclusion7 decks110 decks
6%synergy
Bad Moon
6.4%inclusion7 decks110 decks
3%synergy
Alien Symbiosis
5.6%inclusion4 decks72 decks
5%synergy
Greed
5.5%inclusion6 decks110 decks
-1%synergy
Relic Putrescence
5.5%inclusion6 decks110 decks
5%synergy
Fungal Fortitude
5.5%inclusion6 decks110 decks
4%synergy
Planeswalkers
Liliana of the Dark Realms
42%inclusion46 decks110 decks
28%synergy
Vraska, Betrayal's Sting
38%inclusion42 decks110 decks
36%synergy
Tezzeret, Cruel Captain
5.9%inclusion5 decks85 decks
5%synergy
Utility Lands
Cabal Coffers
80%inclusion88 decks110 decks
25%synergy
Urborg, Tomb of Yawgmoth
75%inclusion82 decks110 decks
37%synergy
Rogue's Passage
58%inclusion64 decks110 decks
39%synergy
Karn's Bastion
47%inclusion52 decks110 decks
43%synergy
Bojuka Bog
37%inclusion41 decks110 decks
-10%synergy
Urza's Saga
35%inclusion38 decks110 decks
27%synergy
Cabal Stronghold
29%inclusion32 decks110 decks
-5%synergy
Nykthos, Shrine to Nyx
27%inclusion30 decks110 decks
-3%synergy
The Black Gate
22%inclusion24 decks110 decks
18%synergy
Lake of the Dead
18%inclusion20 decks110 decks
13%synergy
Phyrexian Tower
15%inclusion17 decks110 decks
-10%synergy
Command Beacon
15%inclusion17 decks110 decks
7%synergy
Castle Locthwain
15%inclusion17 decks110 decks
-1%synergy
Takenuma, Abandoned Mire
15%inclusion16 decks110 decks
-1%synergy
Reliquary Tower
14%inclusion15 decks110 decks
-16%synergy
Cathedral of War
13%inclusion14 decks110 decks
12%synergy
Strip Mine
13%inclusion14 decks110 decks
10%synergy
War Room
11%inclusion12 decks110 decks
-5%synergy
Homeward Path
11%inclusion12 decks110 decks
9%synergy
Minas Morgul, Dark Fortress
9.1%inclusion10 decks110 decks
6%synergy
Deserted Temple
9.1%inclusion10 decks110 decks
5%synergy
Vault of Whispers
7.3%inclusion8 decks110 decks
2%synergy
Temple of the False God
7.3%inclusion8 decks110 decks
-0%synergy
Thespian's Stage
7.3%inclusion8 decks110 decks
2%synergy
Wasteland
6.4%inclusion7 decks110 decks
5%synergy
Emergence Zone
6.4%inclusion7 decks110 decks
3%synergy
Inventors' Fair
6.4%inclusion7 decks110 decks
4%synergy
Mortuary Mire
5.5%inclusion6 decks110 decks
-8%synergy
Crystal Vein
5.5%inclusion6 decks110 decks
3%synergy
Buried Ruin
5.5%inclusion6 decks110 decks
0%synergy
Witch's Cottage
5.5%inclusion6 decks110 decks
-19%synergy
Peat Bog
5.5%inclusion6 decks110 decks
3%synergy
Mana Artifacts
Sol Ring
97%inclusion107 decks110 decks
12%synergy
Arcane Signet
66%inclusion73 decks110 decks
5%synergy
Lotus Petal
39%inclusion43 decks110 decks
32%synergy
Mox Opal
35%inclusion38 decks110 decks
31%synergy
The Soul Stone
32%inclusion25 decks77 decks
17%synergy
Glistening Sphere
29%inclusion32 decks110 decks
28%synergy
Mind Stone
26%inclusion29 decks110 decks
-2%synergy
Mox Diamond
26%inclusion29 decks110 decks
23%synergy
Staff of Compleation
24%inclusion26 decks110 decks
22%synergy
Grim Monolith
22%inclusion24 decks110 decks
19%synergy
Fellwar Stone
22%inclusion24 decks110 decks
8%synergy
Throne of Eldraine
20%inclusion22 decks110 decks
10%synergy
Heraldic Banner
18%inclusion20 decks110 decks
13%synergy
Caged Sun
15%inclusion16 decks110 decks
4%synergy
Thought Vessel
15%inclusion16 decks110 decks
-11%synergy
Charcoal Diamond
13%inclusion14 decks110 decks
-9%synergy
Mox Amber
13%inclusion14 decks110 decks
8%synergy
Extraplanar Lens
9.1%inclusion10 decks110 decks
4%synergy
Thran Dynamo
9.1%inclusion10 decks110 decks
3%synergy
Sceptre of Eternal Glory
8.2%inclusion9 decks110 decks
0%synergy
Mox Jasper
7.8%inclusion8 decks102 decks
8%synergy
Gilded Lotus
7.3%inclusion8 decks110 decks
2%synergy
Everflowing Chalice
6.4%inclusion7 decks110 decks
1%synergy
Patchwork Banner
5.5%inclusion6 decks110 decks
1%synergy
Lands
Swamp
95%inclusion105 decks110 decks
0%synergy
Cavern of Souls
35%inclusion38 decks110 decks
28%synergy
Malakir Rebirth
29%inclusion32 decks110 decks
6%synergy
Gemstone Caverns
24%inclusion26 decks110 decks
19%synergy
Myriad Landscape
15%inclusion17 decks110 decks
-10%synergy
Fell the Profane
15%inclusion16 decks110 decks
-5%synergy
Mirrex
12%inclusion13 decks110 decks
11%synergy
Marsh Flats
11%inclusion12 decks110 decks
7%synergy
Verdant Catacombs
10%inclusion11 decks110 decks
7%synergy
Polluted Delta
10%inclusion11 decks110 decks
6%synergy
Bloodstained Mire
10%inclusion11 decks110 decks
6%synergy
Snow-Covered Swamp
7.3%inclusion8 decks110 decks
1%synergy
Urza's Cave
6.4%inclusion7 decks110 decks
-2%synergy
Command Tower
5.5%inclusion6 decks110 decks
-0%synergy
Talon Gates of Madara
5.5%inclusion6 decks110 decks
4%synergy
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